Histaminergic Angioedema

Paula J. Busse; Tukisa Smith

doi:10.1016/j.iac.2017.03.001

Histaminergic Angioedema

Paula J. Busse, Tukisa Smith

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Angioedema is frequently categorized into histamine- or bradykinin-mediated disease. It is critical to determine the underlying mediator of symptoms as it directs treatment. Histaminergic angioedema is the most frequent cause of angioedema. It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema. The underlying treatments of histamine-mediated angioedema are antihistamines, corticosteroids, and epinephrine.

Original language	English
Pages (from-to)	467-481
Number of pages	15
Journal	Immunology and Allergy Clinics of North America
Volume	37
Issue number	3
DOIs	https://doi.org/10.1016/j.iac.2017.03.001
State	Published - Aug 2017

Keywords

Angioedema
Histamine
Histaminergic
Inducible urticaria
Spontaneous urticaria
Urticaria

Access to Document

10.1016/j.iac.2017.03.001

Cite this

@article{9baf0b79d5b94b9aa2708b3a424212fe,

title = "Histaminergic Angioedema",

abstract = "Angioedema is frequently categorized into histamine- or bradykinin-mediated disease. It is critical to determine the underlying mediator of symptoms as it directs treatment. Histaminergic angioedema is the most frequent cause of angioedema. It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema. The underlying treatments of histamine-mediated angioedema are antihistamines, corticosteroids, and epinephrine.",

keywords = "Angioedema, Histamine, Histaminergic, Inducible urticaria, Spontaneous urticaria, Urticaria",

author = "Busse, {Paula J.} and Tukisa Smith",

note = "Funding Information: Disclosure Statement: P.J. Busse has received consulting fees from Shire and CSL Behring; research funding from Shire and CSL Behring. Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

month = aug,

doi = "10.1016/j.iac.2017.03.001",

language = "English",

volume = "37",

pages = "467--481",

journal = "Immunology and Allergy Clinics of North America",

issn = "0889-8561",

publisher = "W.B. Saunders Ltd",

number = "3",

}

TY - JOUR

T1 - Histaminergic Angioedema

AU - Busse, Paula J.

AU - Smith, Tukisa

N1 - Funding Information: Disclosure Statement: P.J. Busse has received consulting fees from Shire and CSL Behring; research funding from Shire and CSL Behring. Publisher Copyright: © 2017 Elsevier Inc.

PY - 2017/8

Y1 - 2017/8

N2 - Angioedema is frequently categorized into histamine- or bradykinin-mediated disease. It is critical to determine the underlying mediator of symptoms as it directs treatment. Histaminergic angioedema is the most frequent cause of angioedema. It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema. The underlying treatments of histamine-mediated angioedema are antihistamines, corticosteroids, and epinephrine.

AB - Angioedema is frequently categorized into histamine- or bradykinin-mediated disease. It is critical to determine the underlying mediator of symptoms as it directs treatment. Histaminergic angioedema is the most frequent cause of angioedema. It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema. The underlying treatments of histamine-mediated angioedema are antihistamines, corticosteroids, and epinephrine.

KW - Angioedema

KW - Histamine

KW - Histaminergic

KW - Inducible urticaria

KW - Spontaneous urticaria

KW - Urticaria

UR - http://www.scopus.com/inward/record.url?scp=85018887794&partnerID=8YFLogxK

U2 - 10.1016/j.iac.2017.03.001

DO - 10.1016/j.iac.2017.03.001

M3 - Review article

C2 - 28687103

AN - SCOPUS:85018887794

SN - 0889-8561

VL - 37

SP - 467

EP - 481

JO - Immunology and Allergy Clinics of North America

JF - Immunology and Allergy Clinics of North America

IS - 3

ER -

Histaminergic Angioedema

Abstract

Keywords

Access to Document

Fingerprint

Cite this