TY - JOUR
T1 - Hispano-American Brain Bank on Neurodevelopmental Disorders
T2 - An initiative to promote brain banking, research, education, and outreach in the field of neurodevelopmental disorders
AU - Dufour, Brett D.
AU - Albores-Gallo, Lilia
AU - Luna-Muñoz, Jose
AU - Hagerman, Randi
AU - Miquelajauregui, Amaya
AU - Buriticá, Efrain
AU - Saldarriaga, Wilmar
AU - Pacheco-Herrero, Mar
AU - Yris Silvestre-Sosa, Ana
AU - Mazefsky, Carla
AU - Gastgeb, Holly
AU - Kofler, Julia
AU - Casanova, Manuel
AU - Hof, Patrick R.
AU - London, Eric
AU - Hagerman, Paul
AU - Martínez-Cerdeño, Verónica
N1 - Funding Information:
The authors are grateful to the donors and their families. The authors also acknowledge the support of family foundations for distributing information about the CENE to the families. The authors thank Desiree Sanchez for her help with figures. This work was funded by NIH MH094681and Shriners Hospitals.
Funding Information:
The authors are grateful to the donors and their families. The authors also acknowledge the support of family foundations for distributing information about the CENE to the families. The authors thank Desiree Sanchez for her help with figures. This work was funded by NIH MH094681and Shriners Hospitals.
Publisher Copyright:
© 2021 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology
PY - 2022/3
Y1 - 2022/3
N2 - Neurodevelopmental disorders (NDDs) are conditions that present with brain dysfunction due to alterations in the processes of brain development. They present with neuropsychiatric, cognitive, and motor symptoms. Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are two of the most common NDDs. Human brain tissue is a scarce resource that is obtained from postmortem donations. In the case of NDDs, specifically autism, the reduced donation rate of brains prevents researchers to investigate its pathology and fine anatomy. The Hispano-American Brain Bank of Neurodevelopmental Disorders (Banco Hispanoamericano de CErebros de trastornos del NEurodesarrollo) or CENE is a large-scale brain bank for neurodevelopmental disorders in Hispano-America and the US. CENE's objectives are to collect and distribute brains of patients with NDDS, with a focus on ASD and FXS, to perform research, promote education of future scientists, and enhance public awareness about the importance of human tissue availability for scientific research on brain function and disease. CENE has thus far established a bilingual system of nodes and teams in several American countries including California-US, Pennsylvania-US, México, Puerto Rico, Colombia, and Dominican Republic. CENE ensures that postmortem NDD samples used in research better match the world's genetic and ethnic diversity. CENE enables and expands NDD brain research worldwide, particularly with respect to ASD and FXS.
AB - Neurodevelopmental disorders (NDDs) are conditions that present with brain dysfunction due to alterations in the processes of brain development. They present with neuropsychiatric, cognitive, and motor symptoms. Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are two of the most common NDDs. Human brain tissue is a scarce resource that is obtained from postmortem donations. In the case of NDDs, specifically autism, the reduced donation rate of brains prevents researchers to investigate its pathology and fine anatomy. The Hispano-American Brain Bank of Neurodevelopmental Disorders (Banco Hispanoamericano de CErebros de trastornos del NEurodesarrollo) or CENE is a large-scale brain bank for neurodevelopmental disorders in Hispano-America and the US. CENE's objectives are to collect and distribute brains of patients with NDDS, with a focus on ASD and FXS, to perform research, promote education of future scientists, and enhance public awareness about the importance of human tissue availability for scientific research on brain function and disease. CENE has thus far established a bilingual system of nodes and teams in several American countries including California-US, Pennsylvania-US, México, Puerto Rico, Colombia, and Dominican Republic. CENE ensures that postmortem NDD samples used in research better match the world's genetic and ethnic diversity. CENE enables and expands NDD brain research worldwide, particularly with respect to ASD and FXS.
KW - Down syndrome
KW - Fragile X syndrome
KW - Latinoamerica
KW - autism
KW - brain bank
KW - neurodevelopmental disorders
UR - http://www.scopus.com/inward/record.url?scp=85114752952&partnerID=8YFLogxK
U2 - 10.1111/bpa.13019
DO - 10.1111/bpa.13019
M3 - Letter
C2 - 34515386
AN - SCOPUS:85114752952
SN - 1015-6305
VL - 32
JO - Brain Pathology
JF - Brain Pathology
IS - 2
M1 - e13019
ER -