Hirudin and other thrombin inhibitors experimental results and potential clinical applications

Lina Badimon; Alvaro Merino; Juan Badimon; James H. Chesebro; Valentin Fuster

doi:10.1016/1050-1738(91)90032-A

Hirudin and other thrombin inhibitors experimental results and potential clinical applications

Lina Badimon
, Alvaro Merino
, Juan Badimon
, James H. Chesebro
, Valentin Fuster

Research output: Contribution to journal › Short survey › peer-review

21 Scopus citations

Abstract

Thrombosis results from the activation of the hemostatic system by pathologic stimuli. It is a dynamic process that involves various blood cells and proteins, the nature of blood flow, and substrate characteristics. The classic description of the hemostatic system encompasses the coagulation and fibrinolytic systems, the platelets, and the endothelium. Thrombin plays a central role in thrombus formation, interacting with the components of the hemostatic system and vessel wall.

Original language	English
Pages (from-to)	261-267
Number of pages	7
Journal	Trends in Cardiovascular Medicine
Volume	1
Issue number	6
DOIs	https://doi.org/10.1016/1050-1738(91)90032-A
State	Published - Sep 1991
Externally published	Yes

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@article{3cf2465959b3447683c566b2cba0f33a,

title = "Hirudin and other thrombin inhibitors experimental results and potential clinical applications",

abstract = "Thrombosis results from the activation of the hemostatic system by pathologic stimuli. It is a dynamic process that involves various blood cells and proteins, the nature of blood flow, and substrate characteristics. The classic description of the hemostatic system encompasses the coagulation and fibrinolytic systems, the platelets, and the endothelium. Thrombin plays a central role in thrombus formation, interacting with the components of the hemostatic system and vessel wall.",

author = "Lina Badimon and Alvaro Merino and Juan Badimon and Chesebro, \{James H.\} and Valentin Fuster",

note = "Funding Information: L.B. is an Investigator of the Council for Scientific Research of Spain, J.B. is the recipient of an Armenberg Foundation Grant, and A.M. is a recipient of a Fogarty Foundation Fellowship Award.",

year = "1991",

month = sep,

doi = "10.1016/1050-1738(91)90032-A",

language = "English",

volume = "1",

pages = "261--267",

journal = "Trends in Cardiovascular Medicine",

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publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Hirudin and other thrombin inhibitors experimental results and potential clinical applications

AU - Badimon, Lina

AU - Merino, Alvaro

AU - Badimon, Juan

AU - Chesebro, James H.

AU - Fuster, Valentin

N1 - Funding Information: L.B. is an Investigator of the Council for Scientific Research of Spain, J.B. is the recipient of an Armenberg Foundation Grant, and A.M. is a recipient of a Fogarty Foundation Fellowship Award.

PY - 1991/9

Y1 - 1991/9

N2 - Thrombosis results from the activation of the hemostatic system by pathologic stimuli. It is a dynamic process that involves various blood cells and proteins, the nature of blood flow, and substrate characteristics. The classic description of the hemostatic system encompasses the coagulation and fibrinolytic systems, the platelets, and the endothelium. Thrombin plays a central role in thrombus formation, interacting with the components of the hemostatic system and vessel wall.

AB - Thrombosis results from the activation of the hemostatic system by pathologic stimuli. It is a dynamic process that involves various blood cells and proteins, the nature of blood flow, and substrate characteristics. The classic description of the hemostatic system encompasses the coagulation and fibrinolytic systems, the platelets, and the endothelium. Thrombin plays a central role in thrombus formation, interacting with the components of the hemostatic system and vessel wall.

UR - https://www.scopus.com/pages/publications/0026006340

U2 - 10.1016/1050-1738(91)90032-A

DO - 10.1016/1050-1738(91)90032-A

M3 - Short survey

AN - SCOPUS:0026006340

SN - 1050-1738

VL - 1

SP - 261

EP - 267

JO - Trends in Cardiovascular Medicine

JF - Trends in Cardiovascular Medicine

IS - 6

ER -

Hirudin and other thrombin inhibitors experimental results and potential clinical applications

Abstract

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