@article{3b7291f3120a46faa07bb0232e3dd870,
title = "Hippocampal contributions to social and cognitive deficits in autism spectrum disorder",
abstract = "Autism spectrum disorder (ASD) is characterized by hallmark impairments in social functioning. Nevertheless, nonsocial cognition, including hippocampus-dependent spatial reasoning and episodic memory, is also commonly impaired in ASD. ASD symptoms typically emerge between 12 and 24 months of age, a time window associated with critical developmental events in the hippocampus. Despite this temporal overlap and evidence of hippocampal structural abnormalities in ASD individuals, relatively few human studies have focused on hippocampal function in ASD. Herein, we review the existing evidence for the involvement of the hippocampus in ASD and highlight the hippocampus as a promising area of interest for future research in ASD.",
keywords = "cognitive mapping, fMRI, memory, neurodevelopmental disorders, social, spatial",
author = "Banker, {Sarah M.} and Xiaosi Gu and Daniela Schiller and Foss-Feig, {Jennifer H.}",
note = "Funding Information: S.M.B. is supported by the National Institute of Mental Health (Grant No. R01MH122611 ) and Seaver Foundation Fellowship . X.G. is supported by the National Institute of Mental Health (Grant Nos R01MH122611 , R01MH123069 , R21MH120789 , R01MH124115 ), the National Institute on Drug Abuse (Grant Nos R01DA043695 and R21DA049243 ), and The Ream Foundation . D.S. is supported by the National Institute of Mental Health (Grant Nos R01MH122611 , R01MH123069 , and R21MH120789 ) and The Ream Foundation . J.F.-F. is supported by the National Institute of Mental Health (Grant Nos R01MH122611 and R01MH119172 ), the National Institute of Neurological Disorders and Stroke (Grant No. R01NS105845 ), The Ream Foundation , and the Seaver Foundation Rare Disease Program . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = oct,
doi = "10.1016/j.tins.2021.08.005",
language = "English",
volume = "44",
pages = "793--807",
journal = "Trends in Neurosciences",
issn = "0166-2236",
publisher = "Elsevier Ltd.",
number = "10",
}