Heterochromatinization of human X‐ chromosomes: classification of replication profile

A. Babu, S. Chemitiganti, R. S. Verma

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The replication profiles of human X‐chromosomes are studied by RBA‐technique. It is suggested that the late replicating X‐chromosome can be arbitrarily classified into 8 types. Furthermore, data suggest that the individual cells are under self‐control pertaining to the inactivated X‐chromosome. This may reflect that the altered chromatin may not be uniform in the process of inactivation.

Original languageEnglish
Pages (from-to)108-111
Number of pages4
JournalClinical Genetics
Volume30
Issue number2
DOIs
StatePublished - Aug 1986
Externally publishedYes

Keywords

  • Constitutive heterochromatin
  • X‐chromosome
  • heterochromatinization
  • inactivation
  • late replication

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