Herpes encephalitis in monoclonal gammopathy

Jerome J. Graber, Horia Rus, Tracy Zivin-Tutela, Bruce Polsky

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Fever, behavioral changes, and new-onset seizures in a 73-year-old man with a history monoclonal gammopathy of unknown significance (MGUS) was traced to a herpes simplex virus infection. Although herpes encephalitis has not yet been reported in a patient with MGUS, it has been reported in persons with multiple myeloma and plasmacytoma. Immune system abnormalities associated with oncological conditions and MGUS may result in failure to suppress latent herpes virus infection.

Original languageEnglish
Pages (from-to)78-81
Number of pages4
JournalInfections in Medicine
Issue number3
StatePublished - Mar 2009
Externally publishedYes


  • Herpes encephalitis
  • Herpes simplex virus
  • Monoclonal gammopathy


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