Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach

Beshoy Yanny; Adam Winters; Sandra Boutros; Sammy Saab

doi:10.1016/j.cld.2019.07.001

Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach

Beshoy Yanny, Adam Winters, Sandra Boutros, Sammy Saab

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

Hepatic encephalopathy (HE) is an important cause of morbidity and mortality in patients with cirrhosis. The impact of HE on the health care system is similarly profound. The number of hospital admissions for HE has increased in the last 10-year period. HE is a huge burden to the patients, care givers, and the health care system. HE represents a “revolving door” with readmission, severely affects care givers, and has effects on cognition that can persists after liver transplant. This article reviews the current literature to discuss the challenges and diagnostic and therapeutic approaches to HE.

Original language	English
Pages (from-to)	607-623
Number of pages	17
Journal	Clinics in Liver Disease
Volume	23
Issue number	4
DOIs	https://doi.org/10.1016/j.cld.2019.07.001
State	Published - Nov 2019
Externally published	Yes

Keywords

Hepatic encephalopathy
Liver cirrhosis
Portal hypertension
Refractory hepatic encephalopathy

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10.1016/j.cld.2019.07.001

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title = "Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach",

abstract = "Hepatic encephalopathy (HE) is an important cause of morbidity and mortality in patients with cirrhosis. The impact of HE on the health care system is similarly profound. The number of hospital admissions for HE has increased in the last 10-year period. HE is a huge burden to the patients, care givers, and the health care system. HE represents a “revolving door” with readmission, severely affects care givers, and has effects on cognition that can persists after liver transplant. This article reviews the current literature to discuss the challenges and diagnostic and therapeutic approaches to HE.",

keywords = "Hepatic encephalopathy, Liver cirrhosis, Portal hypertension, Refractory hepatic encephalopathy",

author = "Beshoy Yanny and Adam Winters and Sandra Boutros and Sammy Saab",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = nov,

doi = "10.1016/j.cld.2019.07.001",

language = "English",

volume = "23",

pages = "607--623",

journal = "Clinics in Liver Disease",

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T1 - Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach

AU - Yanny, Beshoy

AU - Winters, Adam

AU - Boutros, Sandra

AU - Saab, Sammy

PY - 2019/11

Y1 - 2019/11

N2 - Hepatic encephalopathy (HE) is an important cause of morbidity and mortality in patients with cirrhosis. The impact of HE on the health care system is similarly profound. The number of hospital admissions for HE has increased in the last 10-year period. HE is a huge burden to the patients, care givers, and the health care system. HE represents a “revolving door” with readmission, severely affects care givers, and has effects on cognition that can persists after liver transplant. This article reviews the current literature to discuss the challenges and diagnostic and therapeutic approaches to HE.

AB - Hepatic encephalopathy (HE) is an important cause of morbidity and mortality in patients with cirrhosis. The impact of HE on the health care system is similarly profound. The number of hospital admissions for HE has increased in the last 10-year period. HE is a huge burden to the patients, care givers, and the health care system. HE represents a “revolving door” with readmission, severely affects care givers, and has effects on cognition that can persists after liver transplant. This article reviews the current literature to discuss the challenges and diagnostic and therapeutic approaches to HE.

KW - Hepatic encephalopathy

KW - Liver cirrhosis

KW - Portal hypertension

KW - Refractory hepatic encephalopathy

UR - http://www.scopus.com/inward/record.url?scp=85071480040&partnerID=8YFLogxK

U2 - 10.1016/j.cld.2019.07.001

DO - 10.1016/j.cld.2019.07.001

M3 - Review article

C2 - 31563214

AN - SCOPUS:85071480040

SN - 1089-3261

VL - 23

SP - 607

EP - 623

JO - Clinics in Liver Disease

JF - Clinics in Liver Disease

IS - 4

ER -

Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach

Abstract

Keywords

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