Hepatic Complications of Inflammatory Bowel Disease

Mahmoud Mahfouz, Paul Martin, Andres F. Carrion

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Hepatobiliary disorders are commonly encountered in patients with inflammatory bowel disease (IBD). Although primary sclerosing cholangitis is the stereotypical hepatobiliary disorder associated with IBD, other diseases, including autoimmune hepatitis and nonalcoholic fatty liver disease, also are encountered in this population. Several agents used for treatment of IBD may cause drug-induced liver injury, although severe hepatotoxicity occurs infrequently. Furthermore, reactivation of hepatitis B virus infection may occur in patients with IBD treated with systemic corticosteroids and biologic agents.

Original languageEnglish
Pages (from-to)191-208
Number of pages18
JournalClinics in Liver Disease
Volume23
Issue number2
DOIs
StatePublished - May 2019
Externally publishedYes

Keywords

  • Autoimmune hepatitis
  • Drug-induced liver injury
  • Hepatitis B reactivation
  • Hepatobiliary disorders
  • Inflammatory bowel disease
  • Nonalcoholic fatty liver disease
  • Primary sclerosing cholangitis

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