@article{aab2281563cb4ecc92f5e007bc05ea01,
title = "Hemophilia growth and development study: Baseline neurodevelopmental findings",
abstract = "Reported baseline findings from the neurological assessment component of the Hemophilia Growth and Development Study (HGDS). HIV-positive (HIV+ n = 207) and HIV-negative (HIV-; n = 126) young males with hemophilia ages 6 to 18 years, were enrolled in a prospective study of their growth and development. At baseline, HIV+ and HIV- subjects were not significantly different in test performance. The number of subjects exhibiting below-average performance in three or more areas assessed was about 25% overall. For both groups, mean test scores were within the average range. Academic and adaptive skills were lower than expected based on mean IQ scores, and more behavioral/emotional problems than expected were reported by parents. Absolute CD4 cell counts per mm3 were not related to neuropsychological performance at baseline. Results suggest that the subjects with HIV were relatively free of HIV-related neuropsychological impairment at baseline and that observed differences from a general population reflect effects of hemophilia as a chronic illness",
keywords = "Adjustment, HIV, Hemophilia, Neuropsychology",
author = "Loveland, {Katherine A.} and James Stehbens and Charles Contant and Bordeaux, {Janice D.} and Patricia Sirois and Bell, {Terece S.} and Suzanne Hill and Anthony Scott and Mary Bowman and Marilyn Schiller and John Watkins and Roberta Olson and Patricia Moylan and Valerie Cool and Brain Belden",
note = "Funding Information: 'This research was supported by the Bureau of Maternal and Child Health and Resources Development (MCJ-060570), the National Institute for Child Health and Human Development (NO1-HD-8-2908), the Division of HIV/AIDS of the Centers for Disease Control, and the National Institute of Mental Health. Additional support has been provided by grants from the National Center for Research Resources of the National Institutes of Health to the Mount Sinai General Clinical Research Center, New York (MO1-RROOO71), the University of Iowa Clinical Research Center (MO1-RR00059), and the University of Texas Health Science Center, Houston (MO1-RR02558). We are indebted to the children, adolescents, and parents who have volunteered to participate in this study; to the members of the Hemophilia Treatment Centers, the laboratories at the Centers for Disease Control, and the ^af» maruiyiwiit staff of the New England Research Institute. 3AJI correspondence should be sent to Katherine A. Loveland, Department of Psychiatry and Behavioral Sciences, University of Texas Medical School at Houston, UTMSI, 1300 Moursund Street, Houston, Texas 77030.",
year = "1994",
month = apr,
doi = "10.1093/jpepsy/19.2.223",
language = "English",
volume = "19",
pages = "223--239",
journal = "Journal of Pediatric Psychology",
issn = "0146-8693",
publisher = "Oxford University Press",
number = "2",
}