Hemoperfusion for uremia: Past, present, and future

J. F. Winchester, S. R. Ash

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


This paper will discuss the utility of sorbent hemoperfusion in uremia treatment and will look more critically at the long-term studies, which give some indication of the utility of hemoperfusion, and, finally, will predict the future role of hemoperfusion in uremia therapy. It is certainly clear that the results of the long-term studies of hemoperfusion in uremia suggest that reduction of dialysis time may be achieved with the addition of hemoperfusion to hemodialysis, and that certain symptomatology of uremia may be improved or with reduction in dialysis time may remain unchanged. However, tightly controlled studies are necessary to define the role of charcoal hemoperfusion combined with dialysis in the long-term management of uremia. It is likely that the developments in hemoperfusion in the next 5 to 10 years will see the development of hybrid artificial devices combining sorbent and dialysis/filtration technology and that such devices will be used in the management of clinical uremia.

Original languageEnglish
Pages (from-to)S-127-S-130
JournalKidney International
Issue numberSUPPL. 17
StatePublished - 1985
Externally publishedYes


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