Hemodynamic studies in digitalis-induced A-V dissociation in the dog

A-V dissociation was studied by utilizing the intracardiac phonocardiogram, intracardiac pressure pulses and the electrocardiogram, in dogs that were intentionally overdigitalized with intravenous digoxin. Digitalis is capable of inducing A-V dissociation that can be reversed with potassium chloride. Atrial activity maintains its independence in this arrhythmia. The variable pattern of atrial contraction while the atrioventricular valves are open or closed is demonstrated during A-V dissociation.