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Heme oxygenase-1 mitigates Ferroptosis in renal proximal tubule cells
Oreoluwa Adedoyin
, Ravindra Boddu
, Amie Traylor
, Jeremie M. Lever
, Subhashini Bolisetty
, James F. George
, Anupam Agarwal
Research output
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Article
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peer-review
342
Scopus citations
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Keyphrases
Renal Tubular Epithelial Cells
100%
Heme oxygenase-1 (HO-1)
100%
Ferroptosis
100%
Erastin
35%
Cell Viability
21%
Dose Effect
14%
Acute Kidney Injury
14%
Iron Chelator
14%
RSL3
14%
Cell Death
7%
Glutathione
7%
Metabolic Activity
7%
Protein Level
7%
Co-treatment
7%
Gene Expression Level
7%
Increased Dose
7%
N-acetylcysteine
7%
Antioxidant
7%
Induced Cell Death
7%
Anti-inflammatory Properties
7%
Deferoxamine
7%
Iron Supplementation
7%
Cellular Stress
7%
Anti-apoptotic
7%
Heme oxygenase-1 Gene
7%
Non-apoptotic Cell Death
7%
Cytoprotective Enzymes
7%
Iron Source
7%
Ferric Ammonium Citrate
7%
Ferroptosis Inhibitor
7%
Ferrostatin-1
7%
Ferroptosis Inducer
7%
Pharmacology, Toxicology and Pharmaceutical Science
Heme Oxygenase 1
100%
Ferroptosis
100%
Cell Viability
20%
Iron
20%
Acute Kidney Failure
13%
Iron Chelating Agent
13%
Glutathione
6%
Antiapoptotic
6%
Anti-Inflammatory Drug
6%
Acetylcysteine
6%
Antioxidant
6%
Deferoxamine
6%
Cytoprotective Agent
6%
Ferric Ammonium Citrate
6%
Chondroitin Sulfate Iron
6%