Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Irene Ramos; Mena Mansour; Teddy J. Wohlbold; Megan E. Ermler; Ariana Hirsh; Jonathan A. Runstadler; Ana Fernandez-Sesma; Florian Krammer

doi:10.3201/eid2107.141755

Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Irene Ramos
, Mena Mansour
, Teddy J. Wohlbold
, Megan E. Ermler
, Ariana Hirsh
, Jonathan A. Runstadler
, Ana Fernandez-Sesma
, Florian Krammer

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

Original language	English
Pages (from-to)	1197-1201
Number of pages	5
Journal	Emerging Infectious Diseases
Volume	21
Issue number	7
DOIs	https://doi.org/10.3201/eid2107.141755
State	Published - 2015

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title = "Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus",

abstract = "Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.",

author = "Irene Ramos and Mena Mansour and Wohlbold, \{Teddy J.\} and Ermler, \{Megan E.\} and Ariana Hirsh and Runstadler, \{Jonathan A.\} and Ana Fernandez-Sesma and Florian Krammer",

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language = "English",

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T1 - Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

AU - Ramos, Irene

AU - Mansour, Mena

AU - Wohlbold, Teddy J.

AU - Ermler, Megan E.

AU - Hirsh, Ariana

AU - Runstadler, Jonathan A.

AU - Fernandez-Sesma, Ana

AU - Krammer, Florian

PY - 2015

Y1 - 2015

N2 - Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

AB - Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

UR - https://www.scopus.com/pages/publications/84931365600

U2 - 10.3201/eid2107.141755

DO - 10.3201/eid2107.141755

M3 - Article

C2 - 26079843

AN - SCOPUS:84931365600

SN - 1080-6040

VL - 21

SP - 1197

EP - 1201

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 7

ER -

Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Abstract

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