Halogen halos: Report of an early histopathologic finding in iododerma

Avi Bitterman, Melissa Peri Zundell, Corinna Psomadakis, Israel Kasago, Robert Phelps, George Niedt, Saakshi Khattri

Research output: Contribution to journalArticlepeer-review


Iododerma is a rare cutaneous eruption that manifests after exposure to iodine-containing compounds, with few cases reported in the literature. Previous reports of this halogenoderma have described acellular halos simulating cryptococcus on histopathological examination but there is a paucity of reports of biopsies taken early in the disease course. We present a case of a 78-year-old patient who developed a papular eruption after receiving iodinated contrast. A skin biopsy taken within 24 h of the eruption showed a neutrophilic infiltrate with cryptococcal-like acellular haloed structures, indicating that the diagnostic finding may be found early in the disease course.

Original languageEnglish
JournalJournal of Cutaneous Pathology
StateAccepted/In press - 2023


  • halogen halos
  • halogenoderma
  • iododerma


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