Gynecologic Disorders in Women With Ehlers-Danlos Syndrome

Lisa J. McIntosh, Veronica T. Mallett, Jane D. Frahm, David A. Richardson, Mark I. Evans

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Objective: We characterized the population with Ehlers-Danlos syndrome with regard to genital prolapse, urinary incontinence, and otehr gynecologic disorders. Methods: Forty-one adult women who had registered for a first-ever Ehlers-Danlos multidisciplinary clinic participated in the study. Each had a comprehensive standardized evaluation, including gynecologic history, physical examination, urodynamic testing, and physical therapy evaluation. Qualitative and quantitative data were analyzed to determine means for various gynecologic disorders of Ehlers-Danlos syndrome. Results: The frequencies of incontinence complaints (59%), endometriosis (27%), dyspareunia (57%), and previous hysterectomy (44%) were higher than expected for a population with a mean age of 41 years. Incontinence could not be demonstrated objectively. Prolapse was diagnosed in 12 (29.3%). Conclusions: Careful attention should be paid to women with Ehlers-Danlos syndrome because of an association with many gynecologic complaints. Women with Ehlers-Danlos syndrome should be questioned regarding incontinence, genital prolapse, endometriosis, and dyspareunia.

Original languageEnglish
Pages (from-to)559-564
Number of pages6
JournalJournal of the Society for Gynecologic Investigation
Volume2
Issue number3
DOIs
StatePublished - May 1995
Externally publishedYes

Keywords

  • Ehlers-Danlos syndrome
  • dyspareunia
  • endometriosis
  • genital prolapse
  • urinary incontinence

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