Growth factor signaling in the regulation of prostate growth

Jason Bylund; Anastasios Tahmatzopoulos; Natasha Kyprianou

Growth factor signaling in the regulation of prostate growth

Jason Bylund, Anastasios Tahmatzopoulos, Natasha Kyprianou

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The regulation of prostate growth and survival is represented by a delicate balance between cell proliferation and apoptosis (programmed cell death). Loss of this growth equilibrium due to increased proliferation and/or reduced apoptosis ultimately results in aberrant, tumorigenic growth. In recent years there has been an explosion in our understanding of the mechanisms underlying this loss of regulatory control, and ongoing work promises to bring new preventive, diagnostic, and therapeutic insights for the management of prostate cancer.

Original language	English
Title of host publication	Prostate Cancer
Subtitle of host publication	Principles and Practice
Publisher	CRC Press
Pages	91-101
Number of pages	11
ISBN (Electronic)	9780203624326
ISBN (Print)	9781841844589
State	Published - 1 Jan 2005

Cite this

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title = "Growth factor signaling in the regulation of prostate growth",

abstract = "The regulation of prostate growth and survival is represented by a delicate balance between cell proliferation and apoptosis (programmed cell death). Loss of this growth equilibrium due to increased proliferation and/or reduced apoptosis ultimately results in aberrant, tumorigenic growth. In recent years there has been an explosion in our understanding of the mechanisms underlying this loss of regulatory control, and ongoing work promises to bring new preventive, diagnostic, and therapeutic insights for the management of prostate cancer.",

author = "Jason Bylund and Anastasios Tahmatzopoulos and Natasha Kyprianou",

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N2 - The regulation of prostate growth and survival is represented by a delicate balance between cell proliferation and apoptosis (programmed cell death). Loss of this growth equilibrium due to increased proliferation and/or reduced apoptosis ultimately results in aberrant, tumorigenic growth. In recent years there has been an explosion in our understanding of the mechanisms underlying this loss of regulatory control, and ongoing work promises to bring new preventive, diagnostic, and therapeutic insights for the management of prostate cancer.

AB - The regulation of prostate growth and survival is represented by a delicate balance between cell proliferation and apoptosis (programmed cell death). Loss of this growth equilibrium due to increased proliferation and/or reduced apoptosis ultimately results in aberrant, tumorigenic growth. In recent years there has been an explosion in our understanding of the mechanisms underlying this loss of regulatory control, and ongoing work promises to bring new preventive, diagnostic, and therapeutic insights for the management of prostate cancer.

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SN - 9781841844589

SP - 91

EP - 101

BT - Prostate Cancer

PB - CRC Press

ER -

Growth factor signaling in the regulation of prostate growth

Abstract

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