Growth Deficits in Children Treated with Desipramine: A Controlled Study

THOMAS SPENCER, JOSEPH BIEDERMAN, VIRGINIA WRIGHT, MARCO DANON

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Using multiple assessment methods, growth deficits in weight and height were examined in a clinical sample of children and adolescents with attention deficit hyperactivity disorder treated chronically (mean 14 months) with desipramine (DMI) and two comparison samples of children treated chronically with methylphenidate (MPH) and a not-treated group. Although there were statistically significant weight deficits in children treated with both DMI and MPH compared with normal controls, only those treated with MPH sustained height deficits that attained statistical significance. It appears that DMI may be an appropriate alternative for patients with stimulant-associated severe suppression of growth in height.

Original languageEnglish
Pages (from-to)235-243
Number of pages9
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume31
Issue number2
DOIs
StatePublished - 1992
Externally publishedYes

Keywords

  • attention-deficit hyperactivity disorder
  • desipramine
  • growth deficits

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