Gram-negative folliculitis is a complication of treatment of acne or rosaceas with long-term oral antibiotics, usually tetracyclines. It is caused by the replacement of the gram-positive flora of the mucous membranes of the nose with gram-negative bacteria, which is spread to the face. Common causative organisms include Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens, Klebsiella, and Proteus mirabilis. Gram-negative folliculitis should be considered in acne patients who have a flare-up of pustular or cystic lesions while on antibiotics and in patients who have no significant improvement of acne lesions after 3–6 months of antibiotic therapy.
|Title of host publication||Acneiform Eruptions in Dermatology|
|Subtitle of host publication||A Differential Diagnosis|
|Publisher||Springer New York|
|Number of pages||5|
|State||Published - 1 Jan 2014|