Graft-versus-host disease

David Pompei; Kathryn J. Russell; Frederick A. Pereira

doi:10.1007/978-1-4614-5031-3_6

Graft-versus-host disease

David Pompei, Kathryn J. Russell, Frederick A. Pereira

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Graft-versus-host disease (GVHD) is a multisystem disorder combining features of both autoimmunity and immunodeficiency. It is a common and serious complication of hematopoietic stem cell transplantation (HSCT), and rarely solid organ transplantation, transfusion, and donor lymphocyte infusion. Because of its complex pathophysiology and diverse clinical manifestations, management of this challenging disease requires a multidisciplinary approach. Skin findings are the most common presenting sign, and they found in all forms of GVHD; therefore, the dermatologist plays an important role in diagnosis and therapy.

Original language	English
Title of host publication	Buka's Emergencies in Dermatology
Publisher	Springer New York
Pages	103-131
Number of pages	29
ISBN (Electronic)	9781461450313
ISBN (Print)	1461450306, 9781461450306
DOIs	https://doi.org/10.1007/978-1-4614-5031-3_6
State	Published - 1 Jul 2012

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Graft-versus-host disease

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