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GPT-4 in Clinical Practice: Assessing Its Capability for Symptom Extraction from Cancer Patient Notes

  • Fatemeh Shah-Mohammadi
  • , Joseph Finkelstein

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

Accurate extraction of patient symptoms and signs from clinical notes is essential for effective diagnosis, treatment planning, and research. In this study, we evaluate the capability of GPT-4, specifically GPT-4o, in extracting symptoms and signs from nursing notes within the MIMIC-III dataset. We experimented with two temperature settings (1 and 0.3) to explore the impact of model diversity and consistency on extraction accuracy. Performance metrics include precision, specificity, recall, and F1-score. The results show that a higher temperature (1) led to more creative and varied outputs, with a mean precision of 79% and specificity of 96%, but also exhibited variability, with a minimum precision of 24%. Conversely, at a lower temperature (0.3), precision was more conservative but dropped significantly, with a mean precision of 45% and minimum of 0%. High recall and specificity at optimal temperature setting indicates that GPT-4 holds promise as an assistive tool in clinical practice for symptom and sign extraction tasks.

Original languageEnglish
Title of host publicationEnvisioning the Future of Health Informatics and Digital Health
EditorsJohn Mantas, Arie Hasman, Emmanouil Zoulias, Konstantinos Karitis, Parisis Gallos, Marianna Diomidous, Spyridon Zogas, Martha Charalampidou
PublisherIOS Press BV
Pages86-90
Number of pages5
ISBN (Electronic)9781643685908
DOIs
StatePublished - 8 Apr 2025
Externally publishedYes
Event2024 International Conference on Informatics, Management, and Technology in Healthcare, ICIMTH 2024 - Virtual, Online
Duration: 13 Dec 2024 → 15 Dec 2024

Publication series

NameStudies in Health Technology and Informatics
Volume323
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference2024 International Conference on Informatics, Management, and Technology in Healthcare, ICIMTH 2024
CityVirtual, Online
Period13/12/24 → 15/12/24

Keywords

  • GPT
  • Symptom extraction
  • Zero-shot learning

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