Glycosaminoglycans from chicken muscular stomach or gizzard

Yin Chen; Megan Reddy; Yanlei Yu; Fuming Zhang; Robert J. Linhardt

doi:10.1007/s10719-016-9737-4

Glycosaminoglycans from chicken muscular stomach or gizzard

Yin Chen, Megan Reddy, Yanlei Yu, Fuming Zhang, Robert J. Linhardt

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (~64 %) of molecular weight 21–22 kDa. Hyaluronan (~24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.

Original language	English
Pages (from-to)	119-126
Number of pages	8
Journal	Glycoconjugate Journal
Volume	34
Issue number	1
DOIs	https://doi.org/10.1007/s10719-016-9737-4
State	Published - 1 Feb 2017
Externally published	Yes

Keywords

Chicken gizzard
Chondroitin sulfate
Compositional analysis
Glycosaminoglycans
Heparan sulfate
Hyaluranan

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10.1007/s10719-016-9737-4

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title = "Glycosaminoglycans from chicken muscular stomach or gizzard",

abstract = "Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (~64 %) of molecular weight 21–22 kDa. Hyaluronan (~24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.",

keywords = "Chicken gizzard, Chondroitin sulfate, Compositional analysis, Glycosaminoglycans, Heparan sulfate, Hyaluranan",

author = "Yin Chen and Megan Reddy and Yanlei Yu and Fuming Zhang and Linhardt, {Robert J.}",

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T1 - Glycosaminoglycans from chicken muscular stomach or gizzard

AU - Chen, Yin

AU - Reddy, Megan

AU - Yu, Yanlei

AU - Zhang, Fuming

AU - Linhardt, Robert J.

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N2 - Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (~64 %) of molecular weight 21–22 kDa. Hyaluronan (~24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.

AB - Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (~64 %) of molecular weight 21–22 kDa. Hyaluronan (~24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.

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KW - Chondroitin sulfate

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KW - Glycosaminoglycans

KW - Heparan sulfate

KW - Hyaluranan

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Glycosaminoglycans from chicken muscular stomach or gizzard

Abstract

Keywords

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