Glucagon, starvation, and the induction of liver enzymes by hydrocortisone

Olga Greengard, George T. Baker

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Glucagon selectively potentiates an effect of hydrocortisone: when injected into adrenalectomized rats it increases fourfold the induction by hydrocortisone of tyrosine transaminase, but not of tryptophan pyrrolase. Glucagon alone doubles the basal level of tyrosine transaminase and decreases that of tryptophan pyrrolase. The effects of glucagon on both enzymes resemble those of starvation.

Original languageEnglish
Pages (from-to)1461-1462
Number of pages2
JournalScience
Volume154
Issue number3755
DOIs
StatePublished - 1966
Externally publishedYes

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