@article{9b7229b4ddde426d97318246e70bbe68,
title = "Genomic strategies for diabetic nephropathy",
abstract = "Insight into the molecular mechanisms that underlie the origin and progression of diabetic nephropathy remains limited in part because conventional research tools have restricted investigators to focus on single genes or isolated pathways. Microarray technologies provide opportunities for evaluating genetic factors and environmental effects at a genomic scale during the pathogenesis of diabetic nephropathy. Despite the enormous power of the microarray technology, there are several pitfalls that need to be considered. This article discusses conceptual, practical, statistical, and logistical considerations for the use of microarrays in studies of experimental and human diabetic renal disease. New knowledge in this field will facilitate new approaches for molecular diagnosis and drug discovery.",
author = "Katalin Susztak and Kumar Sharma and Mario Schiffer and Peter McCue and Emilio Ciccone and B{\"o}ttinger, \{Erwin P.\}",
note = "Funding Information: E.v.B., F.G., A.P., S.B., A.H.J.D., M.v.B., M.K., J.A.J., and E.H. have no conflicts of interest. M.M. is a consultant and speaker for Eli Lilly \& Co, Sanofi and Novo Nordisk; all honoraria are paid to his employer (Amsterdam UMC, location VUMC). D.T. reports grants from ZONMW and from Chiesi Pharmaceuticals. M.N. received an unrestricted investigator-initiated grant from Astra Zeneca on SGLT2i and lipid fluxes. E.F. received consultancy/speaker fees, outside the present work, from Boehringer Ingelheim, Eli Lilly, As-traZeneca, and Sanofi. D.v.R. has acted as a consultant and received honoraria from Boehringer Ingelheim and Lilly, Merck, Novo Funding Information: This trial was funded by AstraZeneca as an investigator-initiated study. The funder had no role in the study design, the analyses or interpretation of the data, or drafting the manuscript. The funder had no role in the decision to submit this manuscript for publication.",
year = "2003",
month = aug,
day = "1",
language = "English",
volume = "14",
pages = "S271--S278",
journal = "Journal of the American Society of Nephrology : JASN",
issn = "1046-6673",
publisher = "Wolters Kluwer Health",
number = "SUPPL. 3",
}