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Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease
The 23andMe Research Team
Friedman Brain Institute
Icahn School of Medicine at Mount Sinai
Nash Family Center for Advanced Circuit Therapeutics
Neurology
Research output
:
Contribution to journal
›
Article
›
peer-review
27
Scopus citations
Overview
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Keyphrases
Parkinson's Disease
100%
Genome-wide Association Study
100%
Penetrance
100%
Leucine-rich Repeat Kinase 2 (LRRK2)
100%
Age of Onset
66%
LRRK2 mutation
66%
CORO1C
33%
Mutation Carriers
22%
Polygenic Risk Score
22%
Significant Predictors
11%
Chromosome 12
11%
Risk Allele
11%
Cox Proportional Hazards Model
11%
Publicly Available
11%
Linear Mixed Model
11%
Co-immunoprecipitation (co-IP)
11%
Disease Susceptibility
11%
Gene Variants
11%
Disease Variants
11%
Chromosome 3
11%
C-Met
11%
Biochemistry, Genetics and Molecular Biology
Penetrance
100%
LRRK2
100%
Polygenic Score
22%
Chromosome 12
11%
Gene Linkage
11%
Allele
11%
Immunoprecipitation
11%
Chromosome 3
11%
Artificial Neural Network
11%
C-Met
11%
Pharmacology, Toxicology and Pharmaceutical Science
Parkinson's Disease
100%
Onset Age
85%
Disease Predisposition
14%
Mixed Model
14%
Immunoprecipitation
14%
Neuroscience
Parkinson's Disease
100%
Chromosome 12
14%
Immunoprecipitation
14%
Chromosome 3
14%
C-Met
14%
Artificial Neural Network
14%