Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice

Donald L. Putman; Kunjuraman T. Nayar; Barbara O'neill; E. Premkumar-Reddy; Jay A. Levy; Richard E. Kouri

doi:10.3181/00379727-173-41634

Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice

Donald L. Putman
, Kunjuraman T. Nayar
, Barbara O'neill
, E. Premkumar-Reddy
, Jay A. Levy
, Richard E. Kouri

Research output: Contribution to journal › Article › peer-review

Abstract

The expression of viral structural polypeptides and the production of infectious xenotropic virus were found to segregate together in NZB, 129/J, and SWR/J mice and in crosses between these strains. The viral p30 protein segregation pattern, as measured by competition radioimmunoassay using extracts of frozen spleens from backcross progeny, indicate that xenotropic murine leukemia virus expression is controlled by two dominant genes.

Original language	English
Pages (from-to)	217-221
Number of pages	5
Journal	Experimental Biology and Medicine
Volume	173
Issue number	2
DOIs	https://doi.org/10.3181/00379727-173-41634
State	Published - Jun 1983
Externally published	Yes

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@article{1c3046226eba41a088a76f36f48f310b,

title = "Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice",

abstract = "The expression of viral structural polypeptides and the production of infectious xenotropic virus were found to segregate together in NZB, 129/J, and SWR/J mice and in crosses between these strains. The viral p30 protein segregation pattern, as measured by competition radioimmunoassay using extracts of frozen spleens from backcross progeny, indicate that xenotropic murine leukemia virus expression is controlled by two dominant genes.",

author = "Putman, \{Donald L.\} and Nayar, \{Kunjuraman T.\} and Barbara O'neill and E. Premkumar-Reddy and Levy, \{Jay A.\} and Kouri, \{Richard E.\}",

note = "Funding Information: This study was supported in part by a contract from The Council for Tobacco Research-USA, Inc., awarded to Microbiological Associates, Bethesda, Maryland.",

year = "1983",

month = jun,

doi = "10.3181/00379727-173-41634",

language = "English",

volume = "173",

pages = "217--221",

journal = "Experimental Biology and Medicine",

issn = "0037-9727",

publisher = "Frontiers Media SA",

number = "2",

}

Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice. / Putman, Donald L.; Nayar, Kunjuraman T.; O'neill, Barbara et al.
In: Experimental Biology and Medicine, Vol. 173, No. 2, 06.1983, p. 217-221.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice

AU - Putman, Donald L.

AU - Nayar, Kunjuraman T.

AU - O'neill, Barbara

AU - Premkumar-Reddy, E.

AU - Levy, Jay A.

AU - Kouri, Richard E.

N1 - Funding Information: This study was supported in part by a contract from The Council for Tobacco Research-USA, Inc., awarded to Microbiological Associates, Bethesda, Maryland.

PY - 1983/6

Y1 - 1983/6

N2 - The expression of viral structural polypeptides and the production of infectious xenotropic virus were found to segregate together in NZB, 129/J, and SWR/J mice and in crosses between these strains. The viral p30 protein segregation pattern, as measured by competition radioimmunoassay using extracts of frozen spleens from backcross progeny, indicate that xenotropic murine leukemia virus expression is controlled by two dominant genes.

AB - The expression of viral structural polypeptides and the production of infectious xenotropic virus were found to segregate together in NZB, 129/J, and SWR/J mice and in crosses between these strains. The viral p30 protein segregation pattern, as measured by competition radioimmunoassay using extracts of frozen spleens from backcross progeny, indicate that xenotropic murine leukemia virus expression is controlled by two dominant genes.

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DO - 10.3181/00379727-173-41634

M3 - Article

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AN - SCOPUS:0020586577

SN - 0037-9727

VL - 173

SP - 217

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JO - Experimental Biology and Medicine

JF - Experimental Biology and Medicine

IS - 2

ER -

Genetics of Xenotropic Virus Expression in Mice. II. Expression of Major Virus Structural Proteins in Crosses Involving NZB/BINJ, SWR/J, and 129/J Strains of Mice

Abstract

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