@article{546a0ee756994a6bb397e4738c5b5055,
title = "Genetics of obsessive-compulsive disorder and related disorders",
abstract = "Twin and family studies support a significant genetic contribution to obsessive-compulsive disorder (OCD) and related disorders, such as chronic tic disorders, trichotillomania, skin-picking disorder, body dysmorphic disorder, and hoarding disorder. Recently, population-based studies and novel laboratory-based methods have confirmed substantial heritability in OCD. Genome-wide association studies and candidate gene association studies have provided information on specific gene variations that may be involved in the pathobiology of OCD, though a substantial portion of the genetic risk architecture remains unknown.",
keywords = "Candidate gene, Familial recurrence, GWAS, Genetics, Heritability, Model system, OCD, Twin study",
author = "Browne, {Heidi A.} and Gair, {Shannon L.} and Scharf, {Jeremiah M.} and Grice, {Dorothy E.}",
note = "Funding Information: Disclosures: J.M. Scharf has received research support from the National Institutes of Health , grants U01 NS40024 and K02 NS085048 and the Tourette Syndrome Association (TSA) and serves on the TSA Scientific Advisory Board. He has received travel support from the TSA and from the European Commission (COST Action BM0905) . D. E. Grice has received research support from the National Institutes of Health, grant R01 MH092516 , the Tourette Syndrome Association (TSA), and the Tourette Syndrome Association of New Jersey . The other authors have no relevant financial or nonfinancial disclosures. ",
year = "2014",
month = sep,
doi = "10.1016/j.psc.2014.06.002",
language = "English",
volume = "37",
pages = "319--335",
journal = "Psychiatric Clinics of North America",
issn = "0193-953X",
publisher = "W.B. Saunders Ltd",
number = "3",
}