Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

Anand Kumar Andiappan; Sriram Narayanan; Rachel A. Myers; Bernett Lee; Maartje A. Nieuwenhuis; Alessandra Nardin; Choon Sik Park; Hyoung Doo Shin; Jeong Hyun Kim; Harm Jan Westra; Lude Franke; Tonu Esko; Andres Metspalu; Yik Ying Teo; Seang Mei Saw; Chiea Chuen Khor; Jianjun Liu; Gerard H. Koppelman; Dirkje S. Postma; Michael Poidinger; John E. Connolly; De Yun Wang; Olaf Rotzschke; Maria A. Curotto De Lafaille; Fook Tim Chew

doi:10.1016/j.jaci.2014.06.028

Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

Anand Kumar Andiappan
, Sriram Narayanan
, Rachel A. Myers
, Bernett Lee
, Maartje A. Nieuwenhuis
, Alessandra Nardin
, Choon Sik Park
, Hyoung Doo Shin
, Jeong Hyun Kim
, Harm Jan Westra
, Lude Franke
, Tonu Esko
, Andres Metspalu
, Yik Ying Teo
, Seang Mei Saw
, Chiea Chuen Khor
, Jianjun Liu
, Gerard H. Koppelman
, Dirkje S. Postma
, Michael Poidinger

John E. Connolly, De Yun Wang, Olaf Rotzschke, Maria A. Curotto De Lafaille, Fook Tim Chew

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Original language	English
Pages (from-to)	556-558.e13
Journal	Journal of Allergy and Clinical Immunology
Volume	135
Issue number	2
DOIs	https://doi.org/10.1016/j.jaci.2014.06.028
State	Published - 1 Feb 2015
Externally published	Yes

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10.1016/j.jaci.2014.06.028

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Andiappan, A. K., Narayanan, S., Myers, R. A., Lee, B., Nieuwenhuis, M. A., Nardin, A., Park, C. S., Shin, H. D., Kim, J. H., Westra, H. J., Franke, L., Esko, T., Metspalu, A., Teo, Y. Y., Saw, S. M., Khor, C. C., Liu, J., Koppelman, G. H., Postma, D. S., ... Chew, F. T. (2015). Genetic variants of inducible costimulator are associated with allergic asthma susceptibility. Journal of Allergy and Clinical Immunology, 135(2), 556-558.e13. https://doi.org/10.1016/j.jaci.2014.06.028

@article{2a498dde29074331ac47bfc1d79d4ae5,

title = "Genetic variants of inducible costimulator are associated with allergic asthma susceptibility",

author = "Andiappan, \{Anand Kumar\} and Sriram Narayanan and Myers, \{Rachel A.\} and Bernett Lee and Nieuwenhuis, \{Maartje A.\} and Alessandra Nardin and Park, \{Choon Sik\} and Shin, \{Hyoung Doo\} and Kim, \{Jeong Hyun\} and Westra, \{Harm Jan\} and Lude Franke and Tonu Esko and Andres Metspalu and Teo, \{Yik Ying\} and Saw, \{Seang Mei\} and Khor, \{Chiea Chuen\} and Jianjun Liu and Koppelman, \{Gerard H.\} and Postma, \{Dirkje S.\} and Michael Poidinger and Connolly, \{John E.\} and Wang, \{De Yun\} and Olaf Rotzschke and \{Curotto De Lafaille\}, \{Maria A.\} and Chew, \{Fook Tim\}",

note = "Funding Information: These studies were supported by A*STAR / SIgN core funding, and grants SIgN-06-006, SIgN-08-020 , and SIgN-10-029 and NMRC/1150/2008 , Singapore. The Dutch Asthma GWAS (DAG) was supported by the Netherlands Asthma Foundation grant AF ( AF 95.09 , AF 98.48 , AF 3.2.02.51 , and AF 3.2.07.015 ) and a grant from the University Medical Center Groningen . Funding Information: Disclosure of potential conflict of interest: B. Lee is employed by the Singapore Immunology Network. A Nardin is employed by, has received research and travel support from, and has a patent pending with the Singapore Immunology Network , Agency for Science and Technology and Research . D. S. Postma has received consultancy fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Takeda, and Teva and has received research support and lecture fees from Chiesi . D. Y. Wang has received research support from the Singapore Ministry of Education Academic Research Fund , Singapore Immunology Network , National Medical Research Council (NMRC) (Singapore), and the Agency for Science Technology and Research (A*STAR) (Singapore) and is employed by the National University of Singapore. F. T. Chew has received research support from the Singapore Ministry of Education Academic Research Fund , Singapore Immunology Network , National Medical Research Council (Singapore), and A*STAR (Singapore); has received consultancy fees from Sime Darby Technology Centre; and is employed by the National University of Singapore. The rest of the authors declare that they have no relevant conflicts of interest. Funding Information: We thank all the volunteers who participated in this study; Ramani Anantharaman, Parate Pallavi Nilkanth, Bani Kaur Suri, Sri Anusha Matta, and Veonice Au Bijin for processing human blood samples; Lucy Robinson of Insight Editing London for English editing; the EVE Consortium ( National Institutes of Health grant no. RC2 HL101651 ) for providing results of their meta-analysis; and Juan J. Lafaille for comments on the manuscript. The Korean asthmatic IgE study was provided by the Soonchunhyang University Bucheon Hospital Biobank, and supported by the Ministry of Health, Welfare and Family Affairs (no. schbc-biobank-2012-004). ",

year = "2015",

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day = "1",

doi = "10.1016/j.jaci.2014.06.028",

language = "English",

volume = "135",

pages = "556--558.e13",

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Andiappan, AK, Narayanan, S, Myers, RA, Lee, B, Nieuwenhuis, MA, Nardin, A, Park, CS, Shin, HD, Kim, JH, Westra, HJ, Franke, L, Esko, T, Metspalu, A, Teo, YY, Saw, SM, Khor, CC, Liu, J, Koppelman, GH, Postma, DS, Poidinger, M, Connolly, JE, Wang, DY, Rotzschke, O, Curotto De Lafaille, MA & Chew, FT 2015, 'Genetic variants of inducible costimulator are associated with allergic asthma susceptibility', Journal of Allergy and Clinical Immunology, vol. 135, no. 2, pp. 556-558.e13. https://doi.org/10.1016/j.jaci.2014.06.028

TY - JOUR

T1 - Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

AU - Andiappan, Anand Kumar

AU - Narayanan, Sriram

AU - Myers, Rachel A.

AU - Lee, Bernett

AU - Nieuwenhuis, Maartje A.

AU - Nardin, Alessandra

AU - Park, Choon Sik

AU - Shin, Hyoung Doo

AU - Kim, Jeong Hyun

AU - Westra, Harm Jan

AU - Franke, Lude

AU - Esko, Tonu

AU - Metspalu, Andres

AU - Teo, Yik Ying

AU - Saw, Seang Mei

AU - Khor, Chiea Chuen

AU - Liu, Jianjun

AU - Koppelman, Gerard H.

AU - Postma, Dirkje S.

AU - Poidinger, Michael

AU - Connolly, John E.

AU - Wang, De Yun

AU - Rotzschke, Olaf

AU - Curotto De Lafaille, Maria A.

AU - Chew, Fook Tim

N1 - Funding Information: These studies were supported by A*STAR / SIgN core funding, and grants SIgN-06-006, SIgN-08-020 , and SIgN-10-029 and NMRC/1150/2008 , Singapore. The Dutch Asthma GWAS (DAG) was supported by the Netherlands Asthma Foundation grant AF ( AF 95.09 , AF 98.48 , AF 3.2.02.51 , and AF 3.2.07.015 ) and a grant from the University Medical Center Groningen . Funding Information: Disclosure of potential conflict of interest: B. Lee is employed by the Singapore Immunology Network. A Nardin is employed by, has received research and travel support from, and has a patent pending with the Singapore Immunology Network , Agency for Science and Technology and Research . D. S. Postma has received consultancy fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Takeda, and Teva and has received research support and lecture fees from Chiesi . D. Y. Wang has received research support from the Singapore Ministry of Education Academic Research Fund , Singapore Immunology Network , National Medical Research Council (NMRC) (Singapore), and the Agency for Science Technology and Research (A*STAR) (Singapore) and is employed by the National University of Singapore. F. T. Chew has received research support from the Singapore Ministry of Education Academic Research Fund , Singapore Immunology Network , National Medical Research Council (Singapore), and A*STAR (Singapore); has received consultancy fees from Sime Darby Technology Centre; and is employed by the National University of Singapore. The rest of the authors declare that they have no relevant conflicts of interest. Funding Information: We thank all the volunteers who participated in this study; Ramani Anantharaman, Parate Pallavi Nilkanth, Bani Kaur Suri, Sri Anusha Matta, and Veonice Au Bijin for processing human blood samples; Lucy Robinson of Insight Editing London for English editing; the EVE Consortium ( National Institutes of Health grant no. RC2 HL101651 ) for providing results of their meta-analysis; and Juan J. Lafaille for comments on the manuscript. The Korean asthmatic IgE study was provided by the Soonchunhyang University Bucheon Hospital Biobank, and supported by the Ministry of Health, Welfare and Family Affairs (no. schbc-biobank-2012-004).

PY - 2015/2/1

Y1 - 2015/2/1

UR - https://www.scopus.com/pages/publications/84922344163

U2 - 10.1016/j.jaci.2014.06.028

DO - 10.1016/j.jaci.2014.06.028

M3 - Article

C2 - 25109803

AN - SCOPUS:84922344163

SN - 0091-6749

VL - 135

SP - 556-558.e13

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 2

ER -