Genetic testing for prostate cancer: Willingness and predictors of interest

Michael A. Diefenbach, Robert A. Schnoll, Suzanne M. Miller, Lisa Brower

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


PURPOSE: As researchers come closer to identifying the genes responsible for prostate cancer, the possibility of genetic testing for men at risk for prostate cancer becomes more likely. This study examined the following: 1) the degree to which men (n = 43) or without (n = 83) a family history of prostate cancer would be interested in genetic testing; and 2) the degree to which interest in testing was associated with demographic, family history, and psychosocial factors. DESCRIPTION OF STUDY: Participants (N = 126) were accrued through patients who had been treated for prostate cancer at Fox Chase Cancer Center (n = 39) and through newspaper advertisement (n = 87). All participants completed a questionnaire sent by mail. RESULTS: Seventy- four percent of men were probably (50%) or definitely (24%) interested in testing. Participants with a family history of prostate cancer reported that they would be willing to pay substantially more for a genetic test compared with those without a family history. Elevated worry about prostate cancer and concerns about treatment-related side effects were associated with greater interest in genetic testing. CLINICAL IMPLICATIONS: Findings demonstrate a need for the development of genetic counseling protocols for at-risk men who are interested in genetic testing, once this test becomes available.

Original languageEnglish
Pages (from-to)82-86
Number of pages5
JournalCancer Practice
Issue number2
StatePublished - Mar 2000
Externally publishedYes


  • Genetic counseling
  • Genetic testing
  • Prostate cancer


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