Genetic diversity and intergenogroup recombination events of sapoviruses detected from feces of pigs in Japan

  • Moegi Kuroda
  • , Tsuneyuki Masuda
  • , Mika Ito
  • , Yuki Naoi
  • , Yen Hai Doan
  • , Kei Haga
  • , Shinobu Tsuchiaka
  • , Mai Kishimoto
  • , Kaori Sano
  • , Tsutomu Omatsu
  • , Yukie Katayama
  • , Mami Oba
  • , Hiroshi Aoki
  • , Toru Ichimaru
  • , Fujiko Sunaga
  • , Itsuro Mukono
  • , Hiroshi Yamasato
  • , Junsuke Shirai
  • , Kazuhiko Katayama
  • , Tetsuya Mizutani
  • Tomoichiro Oka, Makoto Nagai

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Sapoviruses (SaV) are enteric viruses infecting humans and animals. SaVs are highly diverse and are divided into multiple genogroups based on structural protein (VP1) sequences. SaVs detected from pigs belong to eight genogroups (GIII, GV, GVI, GVII, GVIII, GIX, GX, and GXI), but little is known about the SaV genogroup distribution in the Japanese pig population. In the present study, 26 nearly complete genome (> 6000 nucleotide: nt) and three partial sequences (2429 nt, 4364 nt, and 4419 nt in length, including the entire VP1 coding region) of SaV were obtained from one diarrheic and 15 non-diarrheic porcine feces in Japan via a metagenomics approach. Phylogenetic analysis of the complete VP1 amino acid sequence (aa) revealed that 29 porcine SaVs were classified into seven genogroups; GIII (11 strains), GV (1 strain), GVI (3 strains), GVII (6 strains), GVIII (1 strain), GX (3 strains), and GXI (4 strains). This manuscript presents the first nearly complete genome sequences of GX and GXI, and demonstrates novel intergenogroup recombination events.

Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalInfection, Genetics and Evolution
Volume55
DOIs
StatePublished - Nov 2017
Externally publishedYes

Keywords

  • Genogroup
  • Japan
  • Pig
  • Recombination
  • Sapovirus

Fingerprint

Dive into the research topics of 'Genetic diversity and intergenogroup recombination events of sapoviruses detected from feces of pigs in Japan'. Together they form a unique fingerprint.

Cite this