Gender differences in the clinical characteristics and psychiatric comorbidity in patients with antisocial personality disorder

Leo Sher, Larry J. Siever, Marianne Goodman, Margaret McNamara, Erin A. Hazlett, Harold W. Koenigsberg, Antonia S. New

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Gender is an important variable in the study of mental health because of the actual and perceived differences between men and women. Relatively little is known how males and females differ in their manifestations of antisocial personality disorder (ASPD). Demographic and clinical features of 323 participants with ASPD were assessed and recorded. Women had fewer episodes of antisocial behavior involving or not involving police, higher scores on the Childhood Trauma Questionnaire (CTQ) and on Emotional Abuse and Sexual Abuse subscales of the CTQ compared to men. CTQ scores positively correlated with the number of episodes of antisocial behavior involving police in men but not in women. The percentage of patients with comorbid borderline and histrionic personality disorders was higher and the percentage of participants with cocaine use disorder was lower among women compared to men. Comorbid alcohol use disorder was frequent in both groups, while a higher percentage of women had comorbid mood disorders compared to men. Logistic regression analysis demonstrates that CTQ scores, histrionic personality disorder, and antisocial behavior involving the police drive the difference between the groups. Our findings indicate that treatment of individuals with ASPD should focus on the management of comorbid psychiatric disorders.

Original languageEnglish
Article number9163
Pages (from-to)685-689
Number of pages5
JournalPsychiatry Research
Volume229
Issue number3
DOIs
StatePublished - 30 Oct 2015

Keywords

  • Antisocial personality disorder
  • Childhood abuse
  • Gender
  • Mood disorder
  • Substance abuse

Fingerprint

Dive into the research topics of 'Gender differences in the clinical characteristics and psychiatric comorbidity in patients with antisocial personality disorder'. Together they form a unique fingerprint.

Cite this