Gender differences in cortical glucose metabolism in Alzheimer's disease and normal aging

Benjamin V. Siegel, Lina Shihabuddin, Monte S. Buchsbaum, Arnold Starr, Richard J. Haier, Dirceu C. Valladares Neto

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Male Alzheimer's disease patients, studied with 18-fluoro-2-deoxyglucose positron emission tomography while performing a verbal memory test, showed a right-greater-than-left asymmetry of cortical metabolism that tended to be greater than that in healthy, age-matched control subjects. This asymmetry was absent in female patients, preliminarily suggesting a propensity for left hemispheric involvement in the Alzheimer's disease process in males.

Original languageEnglish
Pages (from-to)211-214
Number of pages4
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume8
Issue number2
DOIs
StatePublished - 1996
Externally publishedYes

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