Gender-Affirming Surgery and Cancer: Considerations for Radiation Oncologists for Pelvic Radiation in Transfeminine Patients

Alicia C. Smart, Kevin X. Liu, Jason D. Domogauer, Carlos Rodriguez-Russo, Brianna Jones, Daniel R. Dickstein, Joseph D. Mancias, Ron Y. Shiloh, Anton Wintner, Anthony L. Zietman, Deborah C. Marshall, M. Aiven Dyer, Andrea L. Russo

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Access to gender-affirming surgery is increasing for many transgender and nonbinary people in the United States, and radiation oncologists must be equipped to care for patients who have undergone such surgery in the region of their planned radiation treatment field. There are no guidelines for radiation treatment planning after gender-affirming surgery, and most oncologists do not receive training in the unique needs of transgender people with cancer. We review common gender-affirming genitopelvic surgeries for transfeminine people, including vaginoplasty, labiaplasty, and orchiectomy, and summarize the existing literature on the treatment of cancers of the neovagina, anus, rectum, prostate, and bladder in these patients. We also describe our systematic treatment approach and rationale for pelvic radiation treatment planning.

Original languageEnglish
Pages (from-to)301-311
Number of pages11
JournalInternational Journal of Radiation Oncology Biology Physics
Volume117
Issue number2
DOIs
StatePublished - 1 Oct 2023

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