Gemcitabine associated retinopathy and nephropathy

Alan T. Sheyman, Kenneth J. Wald, Patricia J. Pahk, K. Bailey Freund

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11 Scopus citations


Purpose: To report a case of presumed gemcitabine-induced retinopathy and nephropathy. Methods: Case Report. Retrospective chart review. Results: A 64-year-old woman with a recent diagnosis of metastatic cholangiocarcinoma presented with progressive visual loss and renal failure shortly after the initiation of a chemotherapy regimen which included gemcitabine. Clinical examination and fluorescein angiography showed findings of severe retinal ischemia. Conclusion: Although gemcitabine chemotherapy has been reported to cause a Purtscherlike retinopathy, we propose in our patient a gemcitabine-induced vasculopathy that lead to significant retinal and renal ischemia.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalRetinal Cases and Brief Reports
Issue number2
StatePublished - 2014


  • Gemcitabine retinopathy


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