Gastroparesis

This chapter discusses the background, prevention, diagnosis, treatment, and prognosis of gastroparesis. Symptoms of gastroparesis include nausea, vomiting, abdominal fullness, and early satiety with meals. The presence of significant abdominal pain should prompt investigation for other causes. Marked malnutrition can occur in severe cases. Gastroparesis is often associated with diabetes, but it may also be related to autonomic nerve dysfunction, vagus nerve damage, medications, connective tissue diseases, and infections, or it may be idiopathic. Treatment options center on improving gastric emptying. This can be accomplished by augmenting neuromuscular function and coordination. Pharmacologic, endoscopic, and surgical options can be considered. Dietary modifications and addressing underlying causes are also essential. In severe cases, surgical options should be considered.