Gastric or coeliac vagotomy decreases drinking after peripheral angiotensin II

C. Jerome, G. P. Smith

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


After bilateral subdiaphragmatic vagotomy, rats drank later and less in response to peripherally administered angiotensin II [13]. We attempted to localize this deficit neurologically by performing selective gastric, hepatic or coeliac vagotomies. The drinking responses of such selectively lesioned rats to 0.1 and 1.0 mg·kg-1 angiotensin II (SC) were compared to those of total bilateral vagotomized rats and sham vagotomized rats. Gastric or coeliac vagotomy produced drinking deficits that were similar to those produced by total abdominal vagotomy, but hepatic vagotomy did not. These results demonstrate the importance of abdominal vagal mechanisms in the drinking response to circulating angiotensin II.

Original languageEnglish
Pages (from-to)533-536
Number of pages4
JournalPhysiology and Behavior
Issue number3
StatePublished - Sep 1982
Externally publishedYes


  • Angiotensin II
  • Coeliac vagotomy
  • Drinking deficits
  • Extracellular thirst
  • Gastric vagotomy
  • Hepatic vagotomy
  • Hypertonic saline
  • Intracellular thirst
  • Vagotomy


Dive into the research topics of 'Gastric or coeliac vagotomy decreases drinking after peripheral angiotensin II'. Together they form a unique fingerprint.

Cite this