Abstract
This chapter presents the definition, classification, incidence/prevalence, economic impact, etiology and risk factors, and pathology/pathogenesis of gastric cancer. Gastric adenocarcinoma is an aggressive form of cancer which encompasses a heterogeneous range of tumors with varying biologic behavior. The chapter also includes the potential pitfalls/common errors made regarding diagnosis of disease, diagnostic and treatment algorithms, prevention/management of complications, important scientific studies, evidence-based clinical data, and essential social guidelines for gastric cancer. Although stomach cancers often present at more advanced stages with symptoms such as vomiting, abdominal pain, anorexia, and weight loss, screening is routinely performed only in countries with a high incidence and in high risk populations such as those with hereditary syndromes. Locoregional disease should be treated by a multidisciplinary team with surgical resection as well as chemotherapy or chemoradiotherapy. Metastatic disease is incurable. Systemic therapy can prolong life.
| Original language | English |
|---|---|
| Title of host publication | Oncology |
| Publisher | wiley |
| Pages | 131-138 |
| Number of pages | 8 |
| ISBN (Electronic) | 9781119189596 |
| ISBN (Print) | 9781119189558 |
| DOIs | |
| State | Published - 30 Aug 2019 |
Keywords
- Chemoradiotherapy
- Chemotherapy
- Diagnostic algorithms
- Evidence-based clinical data
- Gastric cancer
- Hereditary syndromes
- Surgical resection
- Systemic therapy
- Treatment algorithms