Gas‐liquid chromatographic determination of relative amounts of 2‐deoxy‐2‐flouro‐D‐glucose and 2‐deoxy‐2‐fluoro‐D‐mannose synthesized from various methods

Chyng‐Yann ‐Y Shiue, Joanna S. Fowler, Alfred P. Wolf, David Alexoff, Robert R. Macgregor

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A column (6 ft × 1/8 in) containing 4% SE‐30 + 6% OV‐210 on Chromosorb W‐HP 80/100 mesh was employed to determine the relative amounts of 2‐deoxy‐2‐fluoro‐D‐glucose (2‐FDG) and 2‐deoxy‐2‐fluoro‐D‐mannose (2‐FPM) synthesized using various methods. The 2‐FDG synthesized from published methods contains 4–56% of 2‐FDM.

Original languageEnglish
Pages (from-to)503-508
Number of pages6
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume22
Issue number5
DOIs
StatePublished - May 1985
Externally publishedYes

Keywords

  • 2‐Deoxy‐2‐fluoro‐D‐glucose
  • 2‐Deoxy‐2‐fluoro‐D‐mannose
  • Electrophilic fluorination
  • Gas‐liquid chromatographic separations

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