Gag gene of mammalian type-C RNA tumour viruses

Mariano Barbacid; John R. Stephenson; Stuart A. Aaronson

doi:10.1038/262554a0

Gag gene of mammalian type-C RNA tumour viruses

Mariano Barbacid
, John R. Stephenson
, Stuart A. Aaronson

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Abstract

The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').

Original language	English
Pages (from-to)	554-559
Number of pages	6
Journal	Nature
Volume	262
Issue number	5569
DOIs	https://doi.org/10.1038/262554a0
State	Published - 1976
Externally published	Yes

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title = "Gag gene of mammalian type-C RNA tumour viruses",

abstract = "The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').",

author = "Mariano Barbacid and Stephenson, \{John R.\} and Aaronson, \{Stuart A.\}",

year = "1976",

doi = "10.1038/262554a0",

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volume = "262",

pages = "554--559",

journal = "Nature",

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T1 - Gag gene of mammalian type-C RNA tumour viruses

AU - Barbacid, Mariano

AU - Stephenson, John R.

AU - Aaronson, Stuart A.

PY - 1976

Y1 - 1976

N2 - The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').

AB - The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').

UR - https://www.scopus.com/pages/publications/0017169639

U2 - 10.1038/262554a0

DO - 10.1038/262554a0

M3 - Article

C2 - 60707

AN - SCOPUS:0017169639

SN - 0028-0836

VL - 262

SP - 554

EP - 559

JO - Nature

JF - Nature

IS - 5569

ER -

Gag gene of mammalian type-C RNA tumour viruses

Abstract

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