Fungal Leadless Pacemaker Endocarditis Managed by Percutaneous Vacuum-Assisted Evacuation of Vegetation, Pacemaker Extraction, and Replacement

Kelly Q. Jia; Frans J. Beerkens; Chi Zhang; Shinobu Itagaki; Srinivas Dukkipati; Vivek Y. Reddy; Daniel R. Musikantow

doi:10.1016/j.jaccas.2024.102586

Fungal Leadless Pacemaker Endocarditis Managed by Percutaneous Vacuum-Assisted Evacuation of Vegetation, Pacemaker Extraction, and Replacement

Kelly Q. Jia, Frans J. Beerkens, Chi Zhang, Shinobu Itagaki, Srinivas Dukkipati, Vivek Y. Reddy, Daniel R. Musikantow

Research output: Contribution to journal › Article › peer-review

Abstract

Leadless cardiac pacemakers (LCPs) mitigate the risks of traditional transvenous devices such as lead fracture and infection. Two LCPs are clinically available, using either a helix or tined active fixation approach. There are rare reports of LCP infection—all involving the tined device. We report the first pathologically confirmed fungal endocarditis involving a helix-based LCP. This was successfully managed by catheter-based mechanical vacuum evacuation of the vegetation, followed by device extraction and replacement.

Original language	English
Article number	102586
Journal	JACC: Case Reports
Volume	29
Issue number	19
DOIs	https://doi.org/10.1016/j.jaccas.2024.102586
State	Published - 2 Oct 2024

Keywords

fungal endocarditis
leadless pacemaker

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10.1016/j.jaccas.2024.102586

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title = "Fungal Leadless Pacemaker Endocarditis Managed by Percutaneous Vacuum-Assisted Evacuation of Vegetation, Pacemaker Extraction, and Replacement",

abstract = "Leadless cardiac pacemakers (LCPs) mitigate the risks of traditional transvenous devices such as lead fracture and infection. Two LCPs are clinically available, using either a helix or tined active fixation approach. There are rare reports of LCP infection—all involving the tined device. We report the first pathologically confirmed fungal endocarditis involving a helix-based LCP. This was successfully managed by catheter-based mechanical vacuum evacuation of the vegetation, followed by device extraction and replacement.",

keywords = "fungal endocarditis, leadless pacemaker",

author = "Jia, {Kelly Q.} and Beerkens, {Frans J.} and Chi Zhang and Shinobu Itagaki and Srinivas Dukkipati and Reddy, {Vivek Y.} and Musikantow, {Daniel R.}",

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AU - Jia, Kelly Q.

AU - Beerkens, Frans J.

AU - Zhang, Chi

AU - Itagaki, Shinobu

AU - Dukkipati, Srinivas

AU - Reddy, Vivek Y.

AU - Musikantow, Daniel R.

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N2 - Leadless cardiac pacemakers (LCPs) mitigate the risks of traditional transvenous devices such as lead fracture and infection. Two LCPs are clinically available, using either a helix or tined active fixation approach. There are rare reports of LCP infection—all involving the tined device. We report the first pathologically confirmed fungal endocarditis involving a helix-based LCP. This was successfully managed by catheter-based mechanical vacuum evacuation of the vegetation, followed by device extraction and replacement.

AB - Leadless cardiac pacemakers (LCPs) mitigate the risks of traditional transvenous devices such as lead fracture and infection. Two LCPs are clinically available, using either a helix or tined active fixation approach. There are rare reports of LCP infection—all involving the tined device. We report the first pathologically confirmed fungal endocarditis involving a helix-based LCP. This was successfully managed by catheter-based mechanical vacuum evacuation of the vegetation, followed by device extraction and replacement.

KW - fungal endocarditis

KW - leadless pacemaker

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SN - 2666-0849

VL - 29

JO - JACC: Case Reports

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IS - 19

M1 - 102586

ER -

Fungal Leadless Pacemaker Endocarditis Managed by Percutaneous Vacuum-Assisted Evacuation of Vegetation, Pacemaker Extraction, and Replacement

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Keywords

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