Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively

Keyphrases

• Thrombospondin-1 (TSP-1) 100%
• Disintegrin 100%
• Anti-metastatic Activity 100%
• Metalloproteinases 100%
• Proactivity 100%
• Overexpression 30%
• Tumor Metastasis 30%
• ADAMTS 23%
• Amphiregulin 23%
• HB-EGF 23%
• Inhibit Tumor 7%
• Metastasis 7%
• Kinase Activation 7%
• Tumor Angiogenesis 7%
• ERK2 7%
• Mammary Carcinoma 7%
• Human Epidermal Growth Factor Receptor 2 (HER2) 7%
• Pulmonary Tumor 7%
• Cleavage Fragments 7%
• Transmembrane 7%
• Tumor Invasion 7%
• ErbB2 7%
• Proteinase 7%
• Pulmonary Metastasis 7%
• Autoproteolytic Cleavage 7%
• Lewis Lung Carcinoma Cells 7%

Biochemistry, Genetics and Molecular Biology

• Metastasis Inhibition 100%
• Metalloproteinase 100%
• Metalloendopeptidase 100%
• Thrombospondin 100%
• Disintegrin 100%
• ADAMTS 23%
• Heparin-Binding EGF-like Growth Factor 23%
• Amphiregulin 23%
• N-Terminus 15%
• C-Terminus 15%
• Kinase 7%
• Phosphotransferase 7%
• Precursor 7%
• Angiogenesis 7%
• Epidermal Growth Factor Receptor 7%
• ErbB 7%
• Protease 7%

Medicine and Dentistry

• Metastasis Inhibition 100%
• ADAMTS1 Protein 100%
• Metastatic Carcinoma 41%
• Amphiregulin 25%
• Heparin Binding Epidermal Growth Factor 25%
• Carboxy Terminal Sequence 16%
• Amino Terminal Sequence 16%
• Phosphotransferase 8%
• Lung Tumor 8%
• Proteinase 8%
• Tumor Angiogenesis 8%
• Precursor 8%
• Metalloproteinase 8%
• Breast Carcinoma 8%
• Lung Metastasis 8%
• Epidermal Growth Factor Receptor 8%
• ErbB 8%
• Thrombospondin 8%
• Lewis Lung Carcinoma Cell 8%