From stem cells to regulatory T cells: A tale of plasticity

Mehek Ningoo; Miguel Fribourg

doi:10.1016/j.stem.2024.05.002

From stem cells to regulatory T cells: A tale of plasticity

Mehek Ningoo
, Miguel Fribourg

Marc and Jennifer Lipschultz Precision Immunology Institute

Research output: Contribution to journal › Comment/debate

1 Scopus citations

Abstract

In this issue, Yano et al.¹ present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach has the potential to address the low Treg cell yields of current ex vivo Treg cell expansion and induction protocols, an unmet challenge for autologous Treg cell treatments.

Original language	English
Pages (from-to)	789-790
Number of pages	2
Journal	Cell Stem Cell
Volume	31
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2024.05.002
State	Published - 6 Jun 2024

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title = "From stem cells to regulatory T cells: A tale of plasticity",

abstract = "In this issue, Yano et al.1 present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach has the potential to address the low Treg cell yields of current ex vivo Treg cell expansion and induction protocols, an unmet challenge for autologous Treg cell treatments.",

author = "Mehek Ningoo and Miguel Fribourg",

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year = "2024",

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TY - JOUR

T1 - From stem cells to regulatory T cells

T2 - A tale of plasticity

AU - Ningoo, Mehek

AU - Fribourg, Miguel

PY - 2024/6/6

Y1 - 2024/6/6

N2 - In this issue, Yano et al.1 present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach has the potential to address the low Treg cell yields of current ex vivo Treg cell expansion and induction protocols, an unmet challenge for autologous Treg cell treatments.

AB - In this issue, Yano et al.1 present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach has the potential to address the low Treg cell yields of current ex vivo Treg cell expansion and induction protocols, an unmet challenge for autologous Treg cell treatments.

UR - https://www.scopus.com/pages/publications/85194578420

U2 - 10.1016/j.stem.2024.05.002

DO - 10.1016/j.stem.2024.05.002

M3 - Comment/debate

AN - SCOPUS:85194578420

SN - 1934-5909

VL - 31

SP - 789

EP - 790

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 6

ER -

From stem cells to regulatory T cells: A tale of plasticity

Abstract

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