FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells

Upendar Reddy G; Anila H. A; Firoj Ali; Nandaraj Taye; Samit Chattopadhyay; Amitava Das

doi:10.1021/acs.orglett.5b02568

FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells

Upendar Reddy G, Anila H. A, Firoj Ali, Nandaraj Taye, Samit Chattopadhyay, Amitava Das

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.

Original language	English
Pages (from-to)	5532-5535
Number of pages	4
Journal	Organic Letters
Volume	17
Issue number	22
DOIs	https://doi.org/10.1021/acs.orglett.5b02568
State	Published - 20 Nov 2015
Externally published	Yes

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title = "FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells",

abstract = "A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.",

author = "{Reddy G}, Upendar and A, {Anila H.} and Firoj Ali and Nandaraj Taye and Samit Chattopadhyay and Amitava Das",

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AU - Reddy G, Upendar

AU - A, Anila H.

AU - Ali, Firoj

AU - Taye, Nandaraj

AU - Chattopadhyay, Samit

AU - Das, Amitava

PY - 2015/11/20

Y1 - 2015/11/20

N2 - A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.

AB - A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.

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SP - 5532

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JO - Organic Letters

JF - Organic Letters

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ER -

FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells

Abstract

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