Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia

Keyphrases

• Microglia 100%
• Gene Products 100%
• FosB 100%
• Microglial Activation 100%
• Excitotoxic 100%
• Complement C5a Receptor 100%
• C5aR1 33%
• Hippocampus 22%
• C5aR2 16%
• Immunoreactivity 11%
• Null Mice 11%
• Kainate 11%
• Transcription Factor 5%
• Gene Expression 5%
• MRNA Level 5%
• Brain Regions 5%
• Wild Mice 5%
• Depressive-like Behavior 5%
• Decreased Expression 5%
• Epilepsy 5%
• Psychiatric Disorders 5%
• Neurodegenerative 5%
• Neurological Disorders 5%
• Morphological Changes 5%
• Truncated Forms 5%
• Alternative Splicing 5%
• Neurotoxicity 5%
• Hippocampal Neurons 5%
• Activator protein-1 (AP-1) 5%
• Glial Cells 5%
• CD68 5%
• Microarray Analysis 5%
• Adult-onset 5%
• Kainate-induced Seizure 5%
• Complement C5a 5%
• Iba1 5%
• Neuroinflammatory Response 5%
• Transcription Factor Complex 5%

Neuroscience

• Microglia 100%
• Gene Product 100%
• C5a Receptor 100%
• Hippocampus 66%
• Complement Component C5a 33%
• FOSB 33%
• Messenger RNA 33%
• Behavior (Neuroscience) 16%
• Mental Disorder 16%
• Gene Expression 16%
• Transcription Factor FosB 16%
• Nervous System Disorder 16%
• Excitotoxicity 16%
• Alternative Splicing 16%
• CD68 16%
• Activator Protein 1 16%
• Receptor 16%
• Brain Region 16%