TY - JOUR
T1 - First trimester screening for Down syndrome in multiple pregnancy
AU - Cleary-Goldman, Jane
AU - Berkowitz, Richard L.
PY - 2005/12
Y1 - 2005/12
N2 - The incidence of twins, triplets, and high-order multiples has increased substantially in the last two decades secondary to fertility treatments and to delayed childbearing. Prenatal diagnosis in these patients is challenging. Options for screening tests are limited. First trimester screening for Down syndrome in patients with multiples appears promising. This paper will review the advantages of first trimester screening in this high-risk patient population.
AB - The incidence of twins, triplets, and high-order multiples has increased substantially in the last two decades secondary to fertility treatments and to delayed childbearing. Prenatal diagnosis in these patients is challenging. Options for screening tests are limited. First trimester screening for Down syndrome in patients with multiples appears promising. This paper will review the advantages of first trimester screening in this high-risk patient population.
KW - First trimester screening
KW - Multiple pregnancy
KW - Nuchal translucency
UR - http://www.scopus.com/inward/record.url?scp=33644929991&partnerID=8YFLogxK
U2 - 10.1053/j.semperi.2006.01.002
DO - 10.1053/j.semperi.2006.01.002
M3 - Review article
C2 - 16533653
AN - SCOPUS:33644929991
SN - 0146-0005
VL - 29
SP - 395
EP - 400
JO - Seminars in Perinatology
JF - Seminars in Perinatology
IS - 6
ER -