Field dynamics in atrioventricular activation. Clinical evidence of a specific field-to-protein interaction

Manel Ballester-Rodés, Francesc Carreras-Costa, Teresa Versyp-Ducaju, Montserrat Ballester-Rodés, Davendra Mehta

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The atrioventricular node (AV) is considered the electrical connection between the atria and ventricles. There is an electrical pause between activation of the atria and the ventricles (PR segment), but to date the mechanism responsible for this interruption remains unclear. The present communication focuses on the hypothesis that magnetic field dynamics could provide the answer. Proof of this hypothesis is that in Wolff-Parkinson-White syndrome, where there is physical connection between the atria and ventricles (bundle of Kent), there is electrical AV continuity, no PR segment is detected, and catheter ablation of the abnormal bundle restores AV discontinuity. Spontaneous initiation of the heart at the level of the sinus node, the pacemaker of the heart, could also be explained via field dynamics. The known transmembrane pacemaker protein CHN4, present in both sinoatrial and AV nodal cells, could interact with field information to provide specificity in an electronic key-to-lock mechanism interaction.

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalMedical Hypotheses
Volume124
DOIs
StatePublished - Mar 2019
Externally publishedYes

Keywords

  • AV conduction
  • Atria
  • Atrioventricular delay
  • Atrioventricular node
  • Cardiac pacemaker
  • Cardiology
  • ECG
  • Electrocardiogram
  • Electromagnetism
  • Fields
  • Heart
  • Preexcitation
  • Quantum fields
  • Sinus node
  • Ventricles
  • Wolff-Parkinson-White

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