29 Scopus citations


Fertilization in mammalian and nonmammalian organisms has many features in common. These features include a final maturation phase for sperm and eggs, species-specific binding of sperm to eggs, penetration by sperm of one or more extracellular coats surrounding eggs, fusion of sperm and eggs, and activation of eggs. Implicit in this are a variety of basic molecular events, including receptor-ligand interactions, signalling cascades, specific proteolysis, and nuclear transformations. Here, several of these events are addressed for fertilization in animals as diverse as starfish and mice.

Original languageEnglish
Pages (from-to)83-86
Number of pages4
JournalDevelopmental Genetics
Issue number2
StatePublished - 1999


  • Acrosomal proteases
  • Acrosome reaction
  • Ca channels
  • Capacitation
  • Chemotaxis
  • Fertilization
  • Nuclear transformation
  • Sperm activation
  • Vilelline envelope
  • Zona pellucida


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