Fatal COVID-19 pulmonary disease involves ferroptosis

Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, Brent R. Stockwell

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Ferroptosis is a form of cell death that has been associated with different diseases. Here the authors describe an association of ferroptosis with COVID-19 pulmonary pathologies in both patient samples and hamster model and suggest that the dysregulation in iron and lipid metabolism could provide targets to reduce pathology.

Original languageEnglish
Article number3816
JournalNature Communications
Volume15
Issue number1
DOIs
StatePublished - Dec 2024

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