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FANCI functions as a repair/apoptosis switch in response to DNA crosslinks
Richa B. Shah
, Jennifer L. Kernan
, Anya van Hoogstraten
, Kiyohiro Ando
, Yuanyuan Li
, Alicia L. Belcher
, Ivy Mininger
, Andrei M. Bussenault
, Renuka Raman
, Ramanagouda Ramanagoudr-Bhojappa
, Tony T. Huang
, Alan D. D'Andrea
, Settara C. Chandrasekharappa
,
Aneel K. Aggarwal
, Ruth Thompson
,
Samuel Sidi
Icahn School of Medicine at Mount Sinai
Medicine - Hematology and Medical Oncology
Graduate School of Biomedical Sciences
Cancer Mechanisms
Environmental Medicine
Friedman Brain Institute
Institute for Exposomic Research
Mount Sinai Tisch Cancer Center
Pharmacological Sciences
Medicine
Stem Cell Biology and Regenerative Medicine
Research output
:
Contribution to journal
›
Article
›
peer-review
13
Scopus citations
Overview
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Keyphrases
Apoptosis
100%
DNA Interstrand Crosslinks
100%
FANCI
100%
PIDD1
66%
Interstrand Crosslink
50%
FANCD2
50%
Damaged Cells
33%
PIDDosome
33%
Interstrand Crosslink Repair
33%
Mitosis
16%
Apoptotic Cell Death
16%
Excision
16%
Ubiquitination
16%
DNA Damage
16%
Failed Repair
16%
Pro-apoptotic Factors
16%
Endonuclease
16%
Apoptotic Pathway
16%
Failed Attempts
16%
Repair Proteins
16%
Eukaryotes
16%
Caspase-2
16%
Bidirectionality
16%
Deubiquitination
16%
RAIDD
16%
Cell Counter
16%
FANCI-FANCD2
16%
Biochemistry, Genetics and Molecular Biology
Crosslinking of DNA
100%
FANCI
100%
Programmed Cell Death
100%
Cross-Link
71%
FANCD2
57%
DNA Damage
14%
Eukaryote
14%
Deubiquitination
14%
Endonuclease
14%
Caspase 2
14%