False-memory syndrome

Ian Staples; Leonid Sher

doi:10.1016/S0140-6736(95)92868-5

False-memory syndrome

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Original language	English
Pages (from-to)	1704-1705
Number of pages	2
Journal	The Lancet
Volume	346
Issue number	8991-8892
DOIs	https://doi.org/10.1016/S0140-6736(95)92868-5
State	Published - 30 Dec 1995
Externally published	Yes

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10.1016/S0140-6736(95)92868-5

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@article{3ac2429740a340b6bcdf204e33995180,

title = "False-memory syndrome",

author = "Ian Staples and Leonid Sher",

note = "Funding Information: SIR-A pH of 5 or less can protect against vaginal infections and sexually transmitted diseases, including AIDS.l,2 Lactobacilli can generate an acidic vaginal pH, and reduce the incidence of urogenital infections.3 We have shown that Lactobacillus casei subsp rhamnosus GR-1 could colonise the vagina.4 We now report that vaginal instillation of GR-1 and L fermentum B-54 in gelatin pessary (> 1 09 viable organisms) weekly for 1 year in ten premenopausal women (mean age 33; not using any spermicidal products) led to the maintenance of an acidic vaginal pH (mean 4-8 [SD 0-5] per patient during each month). The mean pH before the study was 5-0 (0-4). Urinary tract infections, however, still occurred, due to Escherchia coli (6), Streptococcus sp (3), Staphylococcus sp (3), and coliforms (1). The patients had a history of four or more recurrences of urinary tract infections (mean 6-3 per patient) in the previous year, and this dropped to 1-3 (79-4% drop) in the year of study. Lactobacilli GR-1 and B-54 were recovered each month from the vagina of each patient, and their colonisation was highest (mean 18.1 bacteria per vaginal cell, and 4 -1 x 101 viable organisms per mL vaginal sample) when the pH was 5-0. The patients reported no side-effects of treatment. A low pH per se, produced by lactobacillus colonisation of the vagina, does not appear to prevent all urogenital infections from occurring, although a lower rate of urinary tract infections with vaginal lactobacillus colonisation will be an important outcome for some patients. This work was supported by the Medical Research Council and Ontario Ministry of Health in Canada.",

year = "1995",

month = dec,

day = "30",

doi = "10.1016/S0140-6736(95)92868-5",

language = "English",

volume = "346",

pages = "1704--1705",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Ltd.",

number = "8991-8892",

}

TY - JOUR

T1 - False-memory syndrome

AU - Staples, Ian

AU - Sher, Leonid

N1 - Funding Information: SIR-A pH of 5 or less can protect against vaginal infections and sexually transmitted diseases, including AIDS.l,2 Lactobacilli can generate an acidic vaginal pH, and reduce the incidence of urogenital infections.3 We have shown that Lactobacillus casei subsp rhamnosus GR-1 could colonise the vagina.4 We now report that vaginal instillation of GR-1 and L fermentum B-54 in gelatin pessary (> 1 09 viable organisms) weekly for 1 year in ten premenopausal women (mean age 33; not using any spermicidal products) led to the maintenance of an acidic vaginal pH (mean 4-8 [SD 0-5] per patient during each month). The mean pH before the study was 5-0 (0-4). Urinary tract infections, however, still occurred, due to Escherchia coli (6), Streptococcus sp (3), Staphylococcus sp (3), and coliforms (1). The patients had a history of four or more recurrences of urinary tract infections (mean 6-3 per patient) in the previous year, and this dropped to 1-3 (79-4% drop) in the year of study. Lactobacilli GR-1 and B-54 were recovered each month from the vagina of each patient, and their colonisation was highest (mean 18.1 bacteria per vaginal cell, and 4 -1 x 101 viable organisms per mL vaginal sample) when the pH was 5-0. The patients reported no side-effects of treatment. A low pH per se, produced by lactobacillus colonisation of the vagina, does not appear to prevent all urogenital infections from occurring, although a lower rate of urinary tract infections with vaginal lactobacillus colonisation will be an important outcome for some patients. This work was supported by the Medical Research Council and Ontario Ministry of Health in Canada.

PY - 1995/12/30

Y1 - 1995/12/30

UR - http://www.scopus.com/inward/record.url?scp=0029609357&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(95)92868-5

DO - 10.1016/S0140-6736(95)92868-5

M3 - Letter

C2 - 8551841

AN - SCOPUS:0029609357

SN - 0140-6736

VL - 346

SP - 1704

EP - 1705

JO - The Lancet

JF - The Lancet

IS - 8991-8892

ER -