Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry

Masao Koda; Toshitaka Yoshii; Satoru Egawa; Kenichiro Sakai; Kazuo Kusano; Yukihiro Nakagawa; Takashi Hirai; Kanichiro Wada; Keiichi Katsumi; Atsushi Kimura; Takeo Furuya; Satoshi Maki; Narihito Nagoshi; Kota Watanabe; Tsukasa Kanchiku; Yukitaka Nagamoto; Yasushi Oshima; Kei Ando; Hiroaki Nakashima; Masahiko Takahata; Kanji Mori; Hideaki Nakajima; Kazuma Murata; Shunji Matsunaga; Takashi Kaito; Kei Yamada; Sho Kobayashi; Satoshi Kato; Tetsuro Ohba; Satoshi Inami; Shunsuke Fujibayashi; Hiroyuki Katoh; Haruo Kanno; Hiroshi Takahashi; Kengo Fujii; Masayuki Miyagi; Gen Inoue; Masashi Takaso; Shiro Imagama; Yoshiharu Kawaguchi; Katsushi Takeshita; Masaya Nakamura; Morio Matsumoto; Atsushi Okawa; Masashi Yamazaki

doi:10.3390/jcm10215026

Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry

Masao Koda, Toshitaka Yoshii, Satoru Egawa, Kenichiro Sakai, Kazuo Kusano, Yukihiro Nakagawa, Takashi Hirai, Kanichiro Wada, Keiichi Katsumi, Atsushi Kimura, Takeo Furuya, Satoshi Maki, Narihito Nagoshi, Kota Watanabe, Tsukasa Kanchiku, Yukitaka Nagamoto, Yasushi Oshima, Kei Ando, Hiroaki Nakashima, Masahiko TakahataKanji Mori, Hideaki Nakajima, Kazuma Murata, Shunji Matsunaga, Takashi Kaito, Kei Yamada, Sho Kobayashi, Satoshi Kato, Tetsuro Ohba, Satoshi Inami, Shunsuke Fujibayashi, Hiroyuki Katoh, Haruo Kanno, Hiroshi Takahashi, Kengo Fujii, Masayuki Miyagi, Gen Inoue, Masashi Takaso, Shiro Imagama, Yoshiharu Kawaguchi, Katsushi Takeshita, Masaya Nakamura, Morio Matsumoto, Atsushi Okawa, Masashi Yamazaki

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Postoperative neck pain has been reported as an unsolved postoperative complication of surgery for cervical ossification of the posterior longitudinal ligament (OPLL). The aim of the present study was to elucidate factors having a significant association with postoperative deterioration of neck pain in cervical OPLL patients. We studied a cohort of patients in a prospective registry of 478 patients who had undergone cervical spine surgery for cervical OPLL. We excluded those without evaluation of preoperative neck pain. Therefore, 438 patients were included in the present study. Neck pain was evaluated with the visual analogue scale (VAS, 0–100 mm). Postoperative neck pain deterioration was defined as a ≥20 mm increase of VAS neck pain. Patient factors, neurological status, imaging factors and surgical factors were assessed. Univariate analyses followed by multivariate analysis using stepwise logistic regression was performed. Six months after surgery, 50 (11.6%) patients showed postoperative neck pain deterioration and 76 (17.4%) patients showed postoperative neck pain deterioration 2 years after surgery. Six months after surgery, the rate of neck pain deterioration was significantly higher in patients who had undergone posterior surgery. Two years after surgery, the number of levels fused was significantly correlated with neck pain deterioration.

Original language	English
Article number	5026
Journal	Journal of Clinical Medicine
Volume	10
Issue number	21
DOIs	https://doi.org/10.3390/jcm10215026
State	Published - 1 Nov 2021
Externally published	Yes

Keywords

Cervical spine
Neck pain
Ossification of the posterior longitudinal ligament
Surgery

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10.3390/jcm10215026

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Koda, M., Yoshii, T., Egawa, S., Sakai, K., Kusano, K., Nakagawa, Y., Hirai, T., Wada, K., Katsumi, K., Kimura, A., Furuya, T., Maki, S., Nagoshi, N., Watanabe, K., Kanchiku, T., Nagamoto, Y., Oshima, Y., Ando, K., Nakashima, H., ... Yamazaki, M. (2021). Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry. Journal of Clinical Medicine, 10(21), Article 5026. https://doi.org/10.3390/jcm10215026

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title = "Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry",

abstract = "Postoperative neck pain has been reported as an unsolved postoperative complication of surgery for cervical ossification of the posterior longitudinal ligament (OPLL). The aim of the present study was to elucidate factors having a significant association with postoperative deterioration of neck pain in cervical OPLL patients. We studied a cohort of patients in a prospective registry of 478 patients who had undergone cervical spine surgery for cervical OPLL. We excluded those without evaluation of preoperative neck pain. Therefore, 438 patients were included in the present study. Neck pain was evaluated with the visual analogue scale (VAS, 0–100 mm). Postoperative neck pain deterioration was defined as a ≥20 mm increase of VAS neck pain. Patient factors, neurological status, imaging factors and surgical factors were assessed. Univariate analyses followed by multivariate analysis using stepwise logistic regression was performed. Six months after surgery, 50 (11.6%) patients showed postoperative neck pain deterioration and 76 (17.4%) patients showed postoperative neck pain deterioration 2 years after surgery. Six months after surgery, the rate of neck pain deterioration was significantly higher in patients who had undergone posterior surgery. Two years after surgery, the number of levels fused was significantly correlated with neck pain deterioration.",

keywords = "Cervical spine, Neck pain, Ossification of the posterior longitudinal ligament, Surgery",

author = "Masao Koda and Toshitaka Yoshii and Satoru Egawa and Kenichiro Sakai and Kazuo Kusano and Yukihiro Nakagawa and Takashi Hirai and Kanichiro Wada and Keiichi Katsumi and Atsushi Kimura and Takeo Furuya and Satoshi Maki and Narihito Nagoshi and Kota Watanabe and Tsukasa Kanchiku and Yukitaka Nagamoto and Yasushi Oshima and Kei Ando and Hiroaki Nakashima and Masahiko Takahata and Kanji Mori and Hideaki Nakajima and Kazuma Murata and Shunji Matsunaga and Takashi Kaito and Kei Yamada and Sho Kobayashi and Satoshi Kato and Tetsuro Ohba and Satoshi Inami and Shunsuke Fujibayashi and Hiroyuki Katoh and Haruo Kanno and Hiroshi Takahashi and Kengo Fujii and Masayuki Miyagi and Gen Inoue and Masashi Takaso and Shiro Imagama and Yoshiharu Kawaguchi and Katsushi Takeshita and Masaya Nakamura and Morio Matsumoto and Atsushi Okawa and Masashi Yamazaki",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = nov,

day = "1",

doi = "10.3390/jcm10215026",

language = "English",

volume = "10",

journal = "Journal of Clinical Medicine",

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Koda, M, Yoshii, T, Egawa, S, Sakai, K, Kusano, K, Nakagawa, Y, Hirai, T, Wada, K, Katsumi, K, Kimura, A, Furuya, T, Maki, S, Nagoshi, N, Watanabe, K, Kanchiku, T, Nagamoto, Y, Oshima, Y, Ando, K, Nakashima, H, Takahata, M, Mori, K, Nakajima, H, Murata, K, Matsunaga, S, Kaito, T, Yamada, K, Kobayashi, S, Kato, S, Ohba, T, Inami, S, Fujibayashi, S, Katoh, H, Kanno, H, Takahashi, H, Fujii, K, Miyagi, M, Inoue, G, Takaso, M, Imagama, S, Kawaguchi, Y, Takeshita, K, Nakamura, M, Matsumoto, M, Okawa, A & Yamazaki, M 2021, 'Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry', Journal of Clinical Medicine, vol. 10, no. 21, 5026. https://doi.org/10.3390/jcm10215026

Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry. / Koda, Masao; Yoshii, Toshitaka; Egawa, Satoru et al.
In: Journal of Clinical Medicine, Vol. 10, No. 21, 5026, 01.11.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament

T2 - Study of a cohort using a prospective registry

AU - Koda, Masao

AU - Yoshii, Toshitaka

AU - Egawa, Satoru

AU - Sakai, Kenichiro

AU - Kusano, Kazuo

AU - Nakagawa, Yukihiro

AU - Hirai, Takashi

AU - Wada, Kanichiro

AU - Katsumi, Keiichi

AU - Kimura, Atsushi

AU - Furuya, Takeo

AU - Maki, Satoshi

AU - Nagoshi, Narihito

AU - Watanabe, Kota

AU - Kanchiku, Tsukasa

AU - Nagamoto, Yukitaka

AU - Oshima, Yasushi

AU - Ando, Kei

AU - Nakashima, Hiroaki

AU - Takahata, Masahiko

AU - Mori, Kanji

AU - Nakajima, Hideaki

AU - Murata, Kazuma

AU - Matsunaga, Shunji

AU - Kaito, Takashi

AU - Yamada, Kei

AU - Kobayashi, Sho

AU - Kato, Satoshi

AU - Ohba, Tetsuro

AU - Inami, Satoshi

AU - Fujibayashi, Shunsuke

AU - Katoh, Hiroyuki

AU - Kanno, Haruo

AU - Takahashi, Hiroshi

AU - Fujii, Kengo

AU - Miyagi, Masayuki

AU - Inoue, Gen

AU - Takaso, Masashi

AU - Imagama, Shiro

AU - Kawaguchi, Yoshiharu

AU - Takeshita, Katsushi

AU - Nakamura, Masaya

AU - Matsumoto, Morio

AU - Okawa, Atsushi

AU - Yamazaki, Masashi

PY - 2021/11/1

Y1 - 2021/11/1

N2 - Postoperative neck pain has been reported as an unsolved postoperative complication of surgery for cervical ossification of the posterior longitudinal ligament (OPLL). The aim of the present study was to elucidate factors having a significant association with postoperative deterioration of neck pain in cervical OPLL patients. We studied a cohort of patients in a prospective registry of 478 patients who had undergone cervical spine surgery for cervical OPLL. We excluded those without evaluation of preoperative neck pain. Therefore, 438 patients were included in the present study. Neck pain was evaluated with the visual analogue scale (VAS, 0–100 mm). Postoperative neck pain deterioration was defined as a ≥20 mm increase of VAS neck pain. Patient factors, neurological status, imaging factors and surgical factors were assessed. Univariate analyses followed by multivariate analysis using stepwise logistic regression was performed. Six months after surgery, 50 (11.6%) patients showed postoperative neck pain deterioration and 76 (17.4%) patients showed postoperative neck pain deterioration 2 years after surgery. Six months after surgery, the rate of neck pain deterioration was significantly higher in patients who had undergone posterior surgery. Two years after surgery, the number of levels fused was significantly correlated with neck pain deterioration.

AB - Postoperative neck pain has been reported as an unsolved postoperative complication of surgery for cervical ossification of the posterior longitudinal ligament (OPLL). The aim of the present study was to elucidate factors having a significant association with postoperative deterioration of neck pain in cervical OPLL patients. We studied a cohort of patients in a prospective registry of 478 patients who had undergone cervical spine surgery for cervical OPLL. We excluded those without evaluation of preoperative neck pain. Therefore, 438 patients were included in the present study. Neck pain was evaluated with the visual analogue scale (VAS, 0–100 mm). Postoperative neck pain deterioration was defined as a ≥20 mm increase of VAS neck pain. Patient factors, neurological status, imaging factors and surgical factors were assessed. Univariate analyses followed by multivariate analysis using stepwise logistic regression was performed. Six months after surgery, 50 (11.6%) patients showed postoperative neck pain deterioration and 76 (17.4%) patients showed postoperative neck pain deterioration 2 years after surgery. Six months after surgery, the rate of neck pain deterioration was significantly higher in patients who had undergone posterior surgery. Two years after surgery, the number of levels fused was significantly correlated with neck pain deterioration.

KW - Cervical spine

KW - Neck pain

KW - Ossification of the posterior longitudinal ligament

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=85118166797&partnerID=8YFLogxK

U2 - 10.3390/jcm10215026

DO - 10.3390/jcm10215026

M3 - Article

AN - SCOPUS:85118166797

SN - 2077-0383

VL - 10

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 21

M1 - 5026

ER -

Factors significantly associated with postoperative neck pain deterioration after surgery for cervical ossification of the posterior longitudinal ligament: Study of a cohort using a prospective registry

Abstract

Keywords

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